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Prevacid Lawsuit

Takeda Pharmaceuticals’ popular GERD hearetburn drug Prevacid may cause some users to develop severe kidney damage, including nephritis and kidney failure.

Prevacid, a popular heartburn medication used to treat gastroesophageal reflux disease (GERD) and ulcers, has been linked to serious side effects including chronic kidney disease (CKD), renal failure, nephritis, heart attack, bone fractures and more.

Free Confidential Lawsuit Evaluation: If you or a loved one was injured by Prevacid side effects, you should contact our law firm immediately. You may be entitled to compensation by filing a suit against the manufacturer and our lawyers can help.

Update: PPI Acid Reflux Drugs Increase Stomach Cancer Risk by up to 250%, Study Finds

December 1, 2017 – Extended use of PPIs (3 years or more) can elevate your risk of stomach cancer by up to 250%, a new study has found. For short-term treatment, the drugs have proved safe for blockinh stomach acid production. However, for a small percentage of people who carry a bacterium called Helicobacter pylori, the risk of developing stomach cancer increases dramatically when they take a PPI for an extended period of time, the researchers found.

Overview

Manufactured and marketed by Takeda Pharmaceuticals, Prevacid (also called Prevacid NapraPAC) is a heartburn medication used to reduce the amount of stomach acid produced in the body. Prevacid is part of a family of drugs known as proton pump inhibitors (PPI), which are designed to treat gastroesophageal reflux disease and peptic ulcer disease. PPIs like Prevacid are extremely popular and widely used, with doctors writing nearly 115 million prescriptions for the medications each year nationwide.

PPIs and Kidney Disease

Prevacid an other heartburn medications from the PPI class have been linked to an increased risk for chronic kidney disease, according to a study published in JAMA Internal Medicine on Jan. 11, 2016. The researchers suggested that the widespread use of PPIs may be one of the reasons CKD prevalence has risen faster than would be expected from known risk factors, such as type 2 diabetes and high blood pressure (hypertension).

“We note that our study is observational and does not provide evidence of causality,” the authors concluded. “However, a causal relationship between PPI use and CKD could have a considerable public health effect given the widespread extent of use.”

For the study, the researchers looked at rates of kidney disease among 10,482 subjects in the Atherosclerosis Risk in Communities (ARIC) study. Patients were followed up for a median of 13.9 years. At baseline, 322 (3.1%) of test subjects used PPIs regularly. After adjusting for variables, they found that PPI use was associated with a 20-50% increased risk of chronic kidney disease.

PPIs Causing Massive Health Problems: Ring of Fire Video

Chronic Kidney Disease Stages

There are 5 stages of CKD which are based on glomerular filtration rate (GFR), a test that estimates how much blood passes through the glomeruli — tiny filters in the kidneys that filter waste from the blood — each minute:

  • Stage 1 (90+ GFR) – Normal kidney function but urine findings or structural abnormalities or genetic trait point to kidney disease.
  • Stage 2 (60-89 GFR) – Mildly reduced kidney function, and other findings point to kidney disease.
  • Stage 3A (45-59 GFR); Stage 3B (30-44 GFR) – Moderately reduced kidney function.
  • Stage 4 (15-29 GFR) – Severely reduced kidney function.
  • Stage 5 (<15 or on dialysis) – Very severe, or endstage kidney failure (also referred to as established renal failure).

CKD Symptoms

Signs and symptoms of chronic kidney disease include:

  • Little or no urine when you try to urinate
  • Swelling in the legs and feet
  • Loss of appetite
  • Nausea / vomiting
  • Feeling confused, anxious and restless, or sleepy
  • Pain in the back just below the rib cage (flank pain)

Side Effects of Prevacid

  • Acute interstitial nephritis (inflammation of the kidneys)
  • Acute kidney injury
  • Chronic kidney disease (CKD)
  • Kidney failure (renal failure)
  • Heart attack
  • Bone fractures (hip fracture, wrist fracture, spine fracture)
  • Broken bones
  • Low magnesium levels (hypomagnesemia)

PPI Heartburn Medicines Linked to Dermatological Reactions, Study Finds

October 23, 2017 – A case report presented at this year’s meeting of the American College of Gastroenterology found that the proton pump inhibitors pantoprazole (Protonix) and lansoprazole (Prevacid) were linked to 2 distinct dermatological reactions. The case involved a 32-year-old man who was initially prescribed pantoprazole after presenting with dyspepsia-like symptoms.

PPI Kidney Injury Suits Centralized in New Jersey

August 4, 2017 – The U.S. Judicial Panel on Multidistrict Litigation (JPML) on Wednesday ordered that all federally-filed lawsuits involving kidney injuries from PPI heartburn drugs will be consolidated in the District of New Jersey for pretrial handling. The panel’s ruling marked an about-face from it’s previous opinion on the matter, having in February rejected a bid to create an MDL. The reason for the change was due to the litigation’s substantial increase in size since the initial ruling, and because 2 defendants who previously opposed centralization — AstraZeneca and Pfizer — are now in support of it, according to JPML.

Study Finds Increased Risk of Death with PPI Heartburn Medications

July 5, 2017 – Proton pump inhibitors have been linked to a 25% greater risk of death compared to patients who took H2 blockers, according to a study published Monday in BMJ. The study also found that PPI use was linked to a 15% increased death rate compared to patients who took another kind of acid suppressor other than H2 blockers, and that the death rate was 23% higher among PPI users compared to people who took no such medications.

PPIs Linked to Increased Risk of Pneumonia in Dementia Patients

April 5, 2017 – Dementia patients who take proton pump inhibitors have an 89% increased risk of developing pneumonia compared to dementia patients who don’t use the medications, according to a study published last month in the Journal of the American Geriatrics Society. Independent risk factors for pneumonia included age, male gender, underlying cerebrovascular disease, chronic pulmonary disease, congestive heart failure, diabetes mellitus, and antipsychotic use.

PPIs Linked to Increased Risk for Heart Failure, Death

March 23, 2017 – Proton pump inhibitor heartburn medicines have been linked to an increased risk for heart failure and death in patients with coronary artery disease (CAD), according to a recent study published in PLOS ONE. The researchers found that PPIs are commonly used to prevent complications in CAD patients treated with chronic antiplatelet therapy (aspirin, Plavix, Effient); however, when used in this capacity, proton pump inhibitors may increase the risk of adverse health consequences including pneumonia, micronutrient deficiencies, and osteoporosis-related fractures.

MDL Proposed for Prevacid Kidney Damage Lawsuits

October 20, 2016 – Patients who suffered kidney injuries after taking Prevacid and other PPI heartburn medications have filed a request seeking consolidation of the lawsuits in a multidistrict litigation (MDL) in the Middle District of Louisiana. Plaintiffs allege that without the creation of an MDL, there exists “the possibility of inconsistent pretrial rulings exists, especially with respect to the proper scope and extent of discovery, causation, and other factual and legal issues.”

Case Study Finds Heartburn Drugs Increase Risk of Rhabdomyolysis

September 26, 2016 – A new case study suggests that a skeletal muscle disorder known as rhabdomyolysis may be another potential side effect of proton pump inhibitors. The study described a 45-year-old patient who developed the condition shortly after being treated with an intravenous dose of Nexium (esomeprazole) for chest pain. The findings were published in last month’s edition of Medicine.

Acid Reflux Drugs Linked to Brain Problems, Fluid Buildup

September 1, 2016 – A new study has found that proton pump inhibitors may cause loss of brain function (hepatic encephalopathy or “HE”) and fluid buildup in the abdomen (ascites). The study’s original objective was to determine the efficacy of a treatment for ascites. However, they found that PPIs may cause abdominal fluid accumulation and HE, a loss of brain function that occurs when the liver is unable to remove toxins from the blood.

Study Finds Increased Cardiovascular Complications w/ PPI Use

August 19, 2016 – Prevacid and other proton pump inhibitor heartburn medications have already been linked to a number of severe health problems like chronic kidney disease, acute interstitial nephritis and bone fractures. Add cardiovascular complications in patients with heart disease to that list, according to a June study published in the International Journal of Cardiology. The researchers found that prolonged PPI use was associated with an increased risk for anemia, lower weight, a worsening metabolic profile and under-utilization of cardioprotective drugs (like statins and blood pressure drugs).

PPI Heartburn Meds Linked to Kidney Failure…Again

April 14, 2016 – People who use proton pump inhibitors (PPIs) like Prevacid are more likely than those who take histamine H2 receptor blockers (Pepcid, Tagamet, Zantac) to develop kidney disease and renal failure, a new study suggests. The new findings are based on medical records from more than 173,000 VA patients who were prescribed a PPI and over 20,000 other patients who took H2-blockers. Over the course of 5 years, 15% of PPI users developed CKD, versus 11% of those on H2-blockers. After other factors were calculated, PPI users still had a 28% greater risk.

Generic Prevacid (lansoprazole) Recall

On April 15, 2011, the U.S. Food & Drug Administration (FDA) announced that lansoprazole was being recalled after numerous reports that the pills had clogged and jammed medical equipment despite being designed to dissolve when suspended in liquid. A number of patients have even required emergency care after their feeding tubes because clogged by the pills. But despite the nationwide recall, FDA is warning the public that hospitals and pharmacies are not being asked to return the drug and may still have it in stock.

If you are taking Prevacid

If you are 60 or over and have been taking Prevacid for an extended period of time, you are at high risk for long-term side effects. Wrist fractures, hip fractures, and fractures of the spine are serious injuries that can significantly impair your mobility and quality of life. Treatment is usually costly and can often be required for the rest of the victim’s life.

Do I Have a Prevacid Lawsuit?

The Pharmaceutical Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Prevacid lawsuits. We are handling individual litigation nationwide and currently investigating potential settlements in all 50 states.

Free Confidential Case Evaluation: Again, if you were injured by the side effects of a heartburn medication, you should contact our law firm immediately. You may be entitled to a settlement by filing a lawsuit and our lawyers can help.

Free Confidential Case Evaluation

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