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Zofran and Pregnancy

When taken during pregnancy, Zofran may cause severe congenital birth defects.

When taken during pregnancy, the anti-nausea medication Zofran (generic: ondansetron) may cause severe congenital birth defects.

Free Confidential Lawsuit Evaluation: If your child or other loved one was born with a birth defect after the mother took Zofran in pregnancy, you should contact our law firm immediately. You may be entitled to compensation by filing a suit and our lawyers can help.

Update: Cluster of Rare Birth Defects in Washington may be Linked to Zofran

January 4, 2015 – Three counties in Washington State are struggling to explain a dramatic increase in a severe neural tube birth defect called anencephaly by area hospitals over the past 5 years. Anencephaly is so rare that it is usually written off as a fluke, but rates in Yakima, Benton and Franklin counties are so high that researchers have begun to speculate that the use of certain prescription drugs during pregnancy — including Zofran — may be the cause. Click here to learn more.

Zofran and Morning Sickness

Zofran is a prescription medication approved to treat nausea and vomiting associated with chemotherapy, radiation and certain types of surgery. The drug blocks serotonin and increases gastric emptying to prevent illness.

Though Zofran has been studied on fewer than 200 babies and has not gained approval from the U.S. Food & Drug Administration (FDA) to treat morning sickness, more than one million prescriptions of the drug have been filled by pregnant women.

Zofran Birth Defect Studies

In Feb. 2013, a study published in the New England Journal of Medicine (NEJM) found no evidence of birth defects associated with Zofran. However, critics of the study contend that the sample size was too small and the study period too short to accurately determine the risk.

Another group of researchers took a second look at the same Danish registry, expanding the cohort, and concluded that Zofran use during pregnancy doubled the risk of heart defects and increased the risk of general birth defects by 30%.

In June 2014, the Toronto Star published a review of Zofran as an unapproved morning sickness treatment. According to the newspaper, “At least 20 Canadian women treated with ondansetron for vomiting in pregnancy experienced serious suspected side-effects, including two infant deaths and multiple cases of newborns with heart defects and kidney malformations.”

Have Any Medications Been Approved to Treat Morning Sickness?

Yes. In April 2013, Diclegis (generic: doxylamine and vitamin B6) became the first FDA-approved drug to treat nausea and vomiting in pregnancy. Diclegis was originally introduced in 1956, but it was pulled off the market in 1983 amid product liability lawsuits, only to return again with the FDA’s approval.

“Now that a safe and effective drug is available in the United States, there is no reason for women to be exposed to a drug of unproven maternal and fetal safety,” said Canadian physician and medical researcher Dr. Gideon Koren, who was part of the research team that investigated Zofran birth defects.

Do I Have a Zofran and Pregnancy Lawsuit?

The Product Liability & Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Zofran Lawsuits. We are handling individual litigation nationwide and currently accepting new birth defects cases in all 50 states.

Free Confidential Case Evaluation: Again, if your child was harmed by Zofran side effects, you should contact our law firm immediately. You may be entitled to compensation by filing a Zofran Suit and our lawyers can help.

Free Confidential Case Evaluation

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