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Zegerid Interstitial Nephritis Lawsuit

Proton pump inhibitor heartburn medications like Zegerid have been linked to acute interstitial nephritis, a severe complication that affects the interstitium of the kidneys.

Proton pump inhibitor (PPI) heartburn medications like Zegerid have been linked to acute interstitial nephritis (AIN), a severe complication that affects the interstitium of the kidneys.

Free Confidential Lawsuit Evaluation: If you or a loved one was injured, you should contact our law firm immediately. You may be entitled to compensation by filing a suit and our lawyers can help.

What’s the Problem?

Zegerid (omeprazole / sodium bicarbonate) is a combination of a proton pump inhibitor and an antacid that is used to treat ulcers, gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid production. The drug works by reducing the production of acid by blocking an enzyme in the wall of the stomach that produces acid. Unfortunately, this same mechanism of action can also have long-term effects on the kidneys.

Zegerid and Nephritis

The first report linking omeprazole (the active ingredient in Zegerid) to acute interstitial nephritis was published in 1992. By 2001, at least 17 cases of AIN associated with the drug had been reported in the medical literature. Most patients developed symptoms of nephritis within 3 months of beginning treatment with Zegerid, and some went on to develop kidney failure (end-stage renal disease or ESRD). As a result of these problems, the U.S. Food & Drug Administration (FDA) in December 2014 updated Zegerid labels to include a warning about acute interstitial nephritis.

What is Acute Interstitial Nephritis?

AIN is a form of nephritis that affects the interstitium of the kidneys surrounding the tubules. The condition causes a decrease in kidney function, ranging from slightly dysfunctional to complete kidney failure. The time between exposure to Zegerid and the development of symptoms may be anywhere from 5 days to 5 months. Acute interstitial nephritis may also be referred to as tubulo-interstitial nephritis.

Nephritis Symptoms

  • Blood in the urine
  • Fever
  • Increased or decreased urine output
  • Mental status changes (drowsiness, confusion, coma)
  • Nausea, vomiting
  • Rash
  • Swelling of the bod (any area)
  • Weight gain (from retaining fluid)

Treatment

If Zegerid is determined to be the likely cause of acute interstitial nephritis, the only treatment needed may be to quit taking the drug. However, you should never stop taking a medication without talking to your doctor first. AIN caused by other factors may be treated with anti-inflammatory medications. Quick treatment often leads to a full recovery; however, in some patients, interstitial nephritis causes permanent kidney damage before the condition can be diagnosed.

Do I Have a Zegerid Interstitial Nephritis Lawsuit?

The Pharmaceutical Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Zegerid lawsuits. We are handling individual litigation nationwide and currently accepting new nephritis cases in all 50 states.

Free Confidential Case Evaluation: Again, if you were injured by Zegerid side effects, you should contact our law firm immediately. You may be entitled to compensation by filing a suit and we can help.

Free Confidential Case Evaluation

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