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Zantac COVID-19 Risk & Other Side Effects

A recent study has linked a class of heartburn drugs known as proton pump inhibitors (PPIs) to an increased risk for COVID-19 infection. Zantac (generic: ranitidine), a heartburn medication from the H2 blocker class, has not been associated with increased COVID risk. However, ranitidine was recalled nationwide after it was found to be tainted with the cancer-causing impurity NDMA.
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If you or a loved one was diagnosed with cancer after taking NDMA in Zantac, you should contact our lawyers immediately.

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Heartburn Drugs Linked to Heightened COVID Risk: Study

According to a 2020 study published in the American Journal of Gastroenterology [1], PPI heartburn medications may increase a person’s risk of developing COVID-19.

For the study, a research team from Cedars-Sinai Medical Center conducted an online survey involving more than 86,000 people. Of these, more than 53,000 reported abdominal pain or discomfort, acid reflux, heartburn or regurgitation, and answered questions about the medications they took to relieve those symptoms. More than 3,300 of the participants tested positive for COVID-19, the researchers found.

Respondents who said they took PPIs had anywhere from 2 to almost 4 times the risk of developing COVID, compared to patients who did not take the medicines. People taking PPI medications twice a day had a higher risk of infection compared to those taking them once a day, according to the study.

Dr. Brennan Spiegel, editor-in-chief of the American Journal of Gastroenterology and lead author of the study, speculated that the increased COVID risk with PPI medications may be because the drugs reduce stomach acid, and acid is one way the body kills off potentially harmful bacteria and viruses.

“We found a biological gradient where the stronger the medicine, the higher the dose, the higher the effect for COVID-19,” Spiegel said.

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What Problems Does Zantac Cause?

According to the U.S. Food and Drug Administration (FDA), Zantac has been linked to the following serious side effects:

  • Liver cancer
  • Kidney cancer
  • Lung cancer
  • Intestinal cancer
  • Stomach cancer
  • Pancreatic cancer
  • Colon cancer
  • Ovarian cancer
  • Esophageal cancer
  • Testicular cancer
  • Other types of cancer

Related Article: Zantac Side Effects Info

Why Was Zantac Recalled?

In April 2020, the Food and Drug Administration (FDA) requested that all brand name Zantac products and generic ranitidine be withdrawn from the U.S. market because of concerns over levels of the contaminant N-nitrosodimethylamine (NDMA), which can increase with time and temperature, posing a risk of cancer. Patients should be told to discard all products containing ranitidine, FDA said.

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What's the Difference Between Old Zantac and New Zantac?

Zantac returned to pharmacy shelves in early 2022 with a different ingredient called famotidine instead of ranitidine. The new Zantac 360 provides the same relief as the original and has no known link to cancer.

Get a Free Case Evaluation With Our Attorneys

The Pharmaceutical Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in lawsuits. We are handling individual litigation nationwide and currently accepting new Zantac-induced cancer cases in all 50 states.

Again, If you or a loved one was diagnosed with cancer after taking Zantac, you should contact our law firm immediately. You may be entitled to a settlement by filing a suit and we can help.

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