Xarelto is a direct factor Xa inhibitor prescribed for the prophylaxis of deep vein thrombosis (DVT) in patients who have recently undergone knee or hip replacement surgery, and to reduce the risk of stroke in patients who have atrial fibrillation (afib). However, this drug has recently been linked to a number of severe, potentially life-threatening side effects in its short time on the market (Xarelto was approved in July 2011). Reports suggest that Xarelto may increase the risk of stroke – one of the complications the drug is supposed to prevent – in certain patients.
Free Confidential Lawsuit Evaluation: If you or a loved one had a stroke after taking Xarelto, you should contact our law firm immediately. You may be entitled to compensation by filing a suit against the manufacturer and our lawyers can help.
Update: First Xarelto Trial Kicks Off in New Orleans
April 24, 2017 – The first of 4 bellwether trials alleging bleeding side effects from Xarelto is now underway in Louisiana federal court. The complaint was filed by Joseph Boudreaux, who claims he experienced severe internal bleeding less than a month after taking Xarelto for the first time. His injuries required a week-long stay in an ICU, numerous blood transfusions and heart procedures, according to the lawsuit.
What is Xarelto?
Xarelto is manufactured and marketed in a joint partnership between Janssen Pharmaceuticals (a Johnson & Johnson company) and Bayer HealthCare AG. As a relatively new prescription medication, Xarelto was originally approved by the FDA on July 1, 2011 to reduce the risk of DVT in patients who had recently undergone knee or hip replacement surgery. However, the drug received subsequent approval in November 2011 for its ability to reduce the risk of stroke and blood clots in patients with afib.
Rivaroxaban, the main active ingredient contained in Xarelto, is classified as a direct factor Xa inhibitor. Drugs from this class block factor Xa, a protein that helps the blood to clot. The inhibition of factor Xa interrupts the pathway of the blood coagulation cascade, blocking both thrombin formation and the development of thrombi. These mechanisms are intended to prevent the formation of DVT, stroke, and other related complications.
Xarelto & Stroke
Although Xarelto is prescribed to prevent ischemic strokes (strokes caused by blood clots), the drug may actually increase the risk of hemorrhagic stroke (strokes caused by bleeding in the brain). A hemorrhagic stroke, or cerebral hemorrhage, occurs when there is bleeding in the brain that permanently damages brain tissue. Brain hemorrhages can occur spontaneously, but are most often caused by severe head trauma.
During a hemorrhagic stroke, an artery or blood vessel is ruptured and starts leaking blood into brain tissue. This irritates the tissues, causing them to swell, a condition referred to as cerebral edema. The blood may also develop into a mass called a hematoma, which further increases the intracranial pressure. This reduces blood flow to all areas of the brain, which worsens brain damage.
Symptoms of a Hemorrhagic Stroke
According to the New York Times Health Guide, hemorrhagic stroke symptoms may include:
- Change in alertness (level of consciousness)
- Difficulty speaking or understanding others
- Difficulty swallowing
- Difficulty writing or reading
- Loss of coordination
- Loss of balance
- Movement changes, usually on only one side of the body
- Difficulty moving any body part
- Loss of fine motor skills
- Nausea or vomiting
- Sensation changes, usually on only one side of the body
- Decreased sensation
- Numbness or tingling
- Weakness of any body part
- Vision changes
- Decreased vision
- Loss of all or part of vision
Do I Have a Xarelto Stroke Lawsuit?
The Product Liability & Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Xarelto Lawsuits. We are handling individual litigation nationwide and currently accepting new stroke cases in all 50 states.
Free Confidential Case Evaluation: Again, if you or a loved one was injured by Xarelto side effects, you should contact our law firm immediately. You may be entitled to compensation by filing a class action suit and we can help.