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What is Rosiglitazone?

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Rosiglitazone is the active medicine in Avandia that helps control blood sugar levels.

*** Avandia® Labeling Update 2/4/11: The FDA has notified healthcare professionals and patients that information on the cardiovascular risks (including heart attack) of Avandia (rosiglitazone) has been added to the physician labeling and patient Medication Guide. Additionally, the drug labels have been revised to state that rosiglitazone and rosiglitazone-containing medicines should only be used:

  • In patients already being treated with these medicines
  • In patients whose blood sugar cannot be controlled with other anti-diabetic medicines and who, after consulting with their healthcare professional, do not wish to use pioglitazone-containing medicines (Actos, Actoplus Met, Actoplus Met XR, or Duetact).

Important Information About Rosiglitazone

  • Rosiglitazone is for people with type 2 (non-insulin-dependent) diabetes
  • Rosiglitazone is sometimes used in combination with insulin or other medications, but it is not for treating type 1 diabetes.
  • Rosiglitazone is not recommended for use with insulin
  • Rosiglitazone may also be used for other purposes not listed here.

Rosiglitazone Side Effects

Seek emergency medical help if you have any of these signs of allergic reaction:

  • Hives
  • Difficulty breathing
  • Swelling of the face, lips, tongue, or throat

Stop using rosiglitazone and call your doctor at once if you have experienced any of these serious side effects:

  • Feeling short of breath
  • Swelling or rapid weight gain
  • Chest pain or heavy feeling, pain spreading to the arm or shoulder, sweating, general ill feeling
  • Nausea, stomach pain, low fever, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes)
  • Blurred vision
  • Increased thirst or hunger, urinating more than usual
  • Pale skin, easy bruising or bleeding

This is not a complete list of side effects that may occur. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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