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Nexium Kidney Disease Lawsuit Filed in New York

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An Illinois man who allegedly developed chronic kidney disease (CKD) after taking Nexium (generic: esomeprazole) has filed a products liability lawsuit against AstraZeneca in the Eastern District of New York.

Free Confidential Lawsuit Evaluation: If you or a loved one suffered kidney damage after taking Nexium, you should contact our law firm immediately. You may be entitled to compensation by filing a suit against the manufacturer and our lawyers can help.

What’s the Problem?

September 21, 2016 – According to the lawsuit, Nexium is AstraZeneca’s best-selling drug, with sales topping $5.2 billion in 2008 alone. In 2013, over 15 million people in the U.S. filled a prescription for Nexium or another proton pump inhibitor (PPI) heartburn medication at a cost of over $10 billion. However, studies have found that PPIs are widely over-prescribed, with up to 70% of prescriptions having no appropriate indication.

In addition to Nexium, other proton pump inhibitors include:

Several recent studies have found that use of these drugs may increase the risk of long-term kidney damage. In April, research published in the Journal of the American Society of Nephrology (JASN) determined that patients who took PPIs were 28% more likely to develop chronic kidney disease (CKD) compared to patients who took histamine H2 receptor blockers (Pepcid, Tagamet, Zantac). Another recent study published in JAMA Internal Medicine found that PPI users had a 20-50% increased risk of developing CKD compared to non-users.

The new lawsuit was filed on August 26, 2016, in the U.S. District Court for the Eastern District of New York under case number 16-04801. Plaintiff alleges that AstraZeneca was aware of the link between Nexium and kidney disease, yet failed to adequately warn the public and medical communities about this risk.

Do I Have a Nexium Lawsuit?

The Pharmaceutical Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Nexium lawsuits. We are handling individual litigation nationwide and currently accepting new kidney failure and nephritis cases in all 50 states.

Free Case Evaluation: Again, if you were injured by Nexium side effects, you should contact our law firm immediately. You may be entitled to a settlement by filing a suit and we can help.

Nexium Lawsuit Filed in New York

Nexium 20mg

An Illinois man who claims he developed chronic kidney disease after taking Nexium (generic: esomeprazole) has filed a products liability lawsuit against AstraZeneca.

Free Confidential Lawsuit Evaluation: If you or a loved one suffered kidney damage after taking Nexium, you should contact our law firm immediately. You may be entitled to compensation by filing a suit against the manufacturer and our lawyers can help.

What’s the Problem?

September 14, 2016 – According to the lawsuit, Plaintiff George Mullen took Nexium as prescribed from 2006 to 2013. In 2008, he was diagnosed with chronic kidney disease (CKD), a condition that occurs when the kidneys lose their ability to function over time.

The complaint states that in addition to CKD, plaintiff developed other unspecified serious side effects and personal injury which caused him physical pain, mental anguish, diminished quality of life, as well as monetary expenses resulting from ongoing medical treatment. Mullen claims that AstraZeneca failed to adequately warn about the risk of kidney damage from Nexium despite having knowledge about these dangers.

Plaintiff’s allegation that Nexium caused his CKD was backed by numerous studies which have identified links between the use of proton pump inhibitor (PPI) heartburn drugs and kidney damage. In addition to Nexium, other PPIs include:

The association between PPIs and kidney injury was so strong that the U.S. Food & Drug Administration (FDA) issued a warning about the problem in December 2014. Specifically, FDA warned about the risk of acute interstitial nephritis (AIN), an inflammation of the kidneys that can lead to CKD if untreated.

Mullen’s complaint was filed on August 26, 2016 in the U.S. District Court for the Eastern District of New York. Plaintiff is seeking in excess of $10 million in damages.

Do I Have a Nexium Lawsuit?

The Pharmaceutical Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Nexium lawsuits. We are handling individual litigation nationwide and currently accepting new kidney injury cases in all 50 states.

Free Case Evaluation: Again, if you were injured by Nexium side effects, you should contact our law firm immediately. You may be entitled to a settlement by filing a suit and our lawyers can help.

Nexium Lawsuit Filed in Tennessee

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A Tennessee man has filed a products liability lawsuit against AstraZeneca alleging that the heartburn medication Nexium (generic: esomeprazole) caused him to develop permanent, life-threatening injuries.

Free Confidential Lawsuit Evaluation: If you or a loved one suffered kidney damage from Nexium side effects, you should contact our law firm immediately. You may be entitled to compensation by filing a suit and our lawyers can help.

What’s the Problem?

July 6, 2016 – According to the lawsuit, Plaintiff Charles Bowers took Nexium from 2003 to 2008, after which he was diagnosed with acute interstitial nephritis and chronic active interstitial nephritis. As a result of his conditions, Bowers is required to undergo dialysis 3 times per week and needs a kidney transplant to live, according to the complaint.

Nexium is a proton pump inhibitor (PPI) drug used to decrease the amount of acid produced in the stomach.

PPIs are commonly used to treat gastroesophageal reflux disease (GERD) and peptic ulcer disease (PUD). Prilosec (generic: omeprazole) — originally approved as Losec — was the first proton pump inhibitor to hit the U.S. market in 1988. Nexium was approved in 2001 as a second generation PPI, and is marketed as an improvement on Prilosec. Both medications are made by AstraZeneca.

In February 2016, the Journal of the American Medical Association (JAMA) published a study which found that PPIs may significantly increase the risk of chronic kidney disease (CKD). The researchers looked at data on over 10,000 participants in the Atherosclerosis Risk in Communities (ARIC) study, and found that PPI users had a 45% increased risk of CKD compared to patients who did not take the drugs. When the figures were adjusted for demographics, socioeconomic and clinical variables, a 50% increased risk was detected.

Bowers alleges that AstraZeneca knew or should have known about Nexium’s ability to cause severe kidney damage, and failed to warn the public and medical communities about these risks. The complaint was filed in the U.S. District Court, Western District of Tennessee.

Do I Have a Nexium Lawsuit?

The Pharmaceutical Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Nexium lawsuits. We are handling individual litigation nationwide and currently accepting new injury and death cases in all 50 states.

Free Confidential Case Evaluation: Again, if you suffered from chronic kidney disease (CKD), nephritis or renal failure after using Nexium, you should contact our law firm immediately. You may be entitled to a settlement by filing a suit and we can help.

Nexium Linked to Artery Damage: Study

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A new study has found that the proton pump inhibitor (PPI) heartburn medication Nexium may cause artery damage which could lead to an increased risk for kidney failure, heart attack and dementia.

Free Confidential Lawsuit Evaluation: If you or a loved one suffered kidney damage after taking a proton pump inhibitor, you should contact our law firm immediately. You may be entitled to compensation by filing a suit against the manufacturer and our lawyers can help.

What’s the Problem?

June 6, 2016 – For the study, a research team led by John P. Cooke at the Houston Methodist Research Institute exposed endothelial cells — the cells that line the walls of arteries — to Nexium (esomeprazole magnesium), and compared the results to endothelial cells exposed to H2 blocker heartburn medications (Zantac, Pepcid, Tagamet).

The researchers found that cells exposed to H2 blockers showed no signs of aging, while the cells exposed to Nexium had a “fried egg” appearance. Due to the fact that proton pump inhibitors block acid production by impairing parts of cells called lysosomes, “garbage” builds up in the artery cells which causes them to age.

The study also found that vascular cells couldn’t divide or proliferate as well when exposed to Nexium. This makes it difficult for cells to repair wounds in blood vessels, and prevents them from performing tasks that can help prevent heart attack and stroke, according to the researchers.

“I’m perplexed that the pharmaceutical industry didn’t run across this first,” Cooke said. “This is something that should have been apparent a long time ago and should have been investigated.”

Additionally, the endothelial cells exposed to Nexium showed signs of shortening in chromosomes tips known as telomeres. Previous research has associated shortened telomeres to age-related conditions including dementia, cancer and heart disease.

“Our finding that the lining of blood vessels is impaired by proton pump inhibitors is a unifying mechanism for the reports that PPI users are at increased risk for heart attack, stroke and renal failure,” Cooke told the Chicago Tribune.

Cooke also said that one of the main problems with proton pump inhibitors is that patients rarely use them as directed. The U.S. Food & Drug Administration (FDA) has approved PPIs for use only for 4 weeks at a time, 3 times per year. Instead, many patients use the medications nearly constantly without ever taking a break.

Do I Have a Proton Pump Inhibitor Lawsuit?

The Pharmaceutical Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in PPI lawsuits. We are handling individual litigation nationwide and currently accepting new acute kidney injury cases in all 50 states.

Free Confidential Case Evaluation: Again, if you suffered kidney damage or renal failure after taking a PPI heartburn medication, you should contact our law firm immediately. You may be entitled to compensation by filing a suit and we can help.

Nexium Interstitial Nephritis Lawsuit

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Side effects of the heartburn medication Nexium (generic: esomeprazole) may include interstitial nephritis, a kidney disorder that occurs when the spaces between the kidney tubules become swollen and inflamed.

Free Confidential Lawsuit Evaluation: If you or a loved one was injured, you should contact our law firm immediately. You may be entitled to compensation by filing a suit against the manufacturer and our lawyers can help.

Update: Nexium Lawsuit Filed in New York

September 21, 2016 – A man who claims he developed chronic kidney disease (CKD) as a result of taking Nexium has filed a products liability lawsuit (case #16-04801) against AstraZeneca in the U.S. District Court for the Eastern District of New York. Plaintiff alleges that the manufacturer was aware of the link between Nexium and kidney disease, yet failed to adequately about this risk.

What’s the Problem?

According to research published in the journal BMC Nephrology in July 2013, previous studies and numerous biopsy-confirmed case reports have suggested an association between the use of proton pump inhibitor (PPI) drugs like Nexium and acute interstitial nephritis, or AIN. The New England Journal of Medicine (NEJM) in 2006 released information about a case series and literature review that found a link between proton pump inhibitors and the development of AIN. Although many of these patients experienced some degree of recovery of renal function, others suffered permanent kidney damage as a result of PPI use.

FDA Warning

In December 2014, the U.S. Food & Drug Administration (FDA) announced new warnings would be added to the labeling of proton pump inhibitors regarding an increased risk for acute interstitial nephritis.

Acute interstitial nephritis has been observed in patients taking PPIs including Nexium,”  FDA said. “Acute interstitial nephritis may occur at any point during PPI therapy and is generally attributed to idiopathic hypersensitivity reaction. Discontinue Nexium if acute interstitial nephritis develops.”

What is Interstitial Nephritis?

Interstitial nephritis is a kidney disorder that occurs when there is excessive swelling between the kidney tubules. The kidneys filter blood and wastes from the body; kidney tubules reabsorb water and organic compounds, removing substances the body doesn’t need through the urine. Swelling of these tubules can cause a number of kidney symptoms ranging from mild to severe. Interstitial nephritis can be temporary (acute), or it may be long-lasting (chronic) and get worse over time.

Symptoms

Signs and symptoms of interstitial nephritis may include:

  • Blood in the urine
  • Fever
  • Increased or decreased urine output
  • Mental status changes (drowsiness, confusion, coma)
  • Nausea, vomiting
  • Rash
  • Swelling of the bod (any area)
  • Weight gain (from retaining fluid)

Treatment

Treatment for interstitial nephritis depends on what’s causing the problem. If Nexium is determined to be the likely cause, your doctor may recommend switching to a heartburn drug with fewer potential side effects. However, you should never switch or quit taking a medication without talking to your doctor first.

Other things you can do to help treat interstitial nephritis include:
Limiting salt and fluid in the diet can improve swelling and high blood pressure (hypertension).
Limiting protein intake can help control the buildup of wastes in the blood (azotemia) which can lead to symptoms of acute kidney failure.
Corticosteroids or stronger anti-inflammatory drugs can sometimes be helpful in treating the condition.

Do I have a Nexium Interstitial Nephritis Lawsuit?

The Pharmaceutical Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Nexium lawsuits. We are handling individual litigation nationwide and currently accepting new nephritis cases in all 50 states.

Free Confidential Case Evaluation: Again, if you or a loved one was injured by Nexium side effects, you should contact our law firm immediately. You may be entitled to a settlement by filing a suit and we can help.

Nexium Lawsuit Filed in Illinois

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A man from Madison County, Illinois, who allegedly developed kidney failure after taking the proton pump inhibitor drug Nexium (generic: esomeprazole) has filed a class action lawsuit against AstraZeneca.

Free Confidential Lawsuit Evaluation: If you or a loved one has been injured by Nexium side effects, you should contact our law firm immediately. You may be entitled to compensation by filing a suit against the manufacturer and our lawyers can help.

What’s the Problem?

May 9, 2016 – According to the lawsuit (PDF), Plaintiff Harry Mason began taking Nexium in 2006, which ultimately led to his development of kidney failure requiring the need for a kidney transplant. The complaint states that AstraZeneca committed fraud by failing to adequately warn consumers of Nexium side effects. Mason is alleging charges of common law fraud, fraudulent misrepresentation, as well as negligent and intentional infliction of emotional distress against the drugmaker.

“[AstraZeneca has] had notice of serious adverse health outcomes through case reports, clinical studies and post-market surveillance,” the lawsuit states. “Specifically, Defendants had received numerous case reports of kidney injuries in patients that had ingested Nexium by as early as 2004. These reports of numerous kidney injuries put Defendants on notice as to the excessive risks of kidney injuries related to the use of Nexium.”

Mason’s claim is believed to be one of the first in what will likely be a steady stream of litigation alleging side effects from Nexium and other proton pump inhibitors (PPIs). Plaintiffs in these cases allege that if warnings had been provided about the risk of acute interstitial nephritis, chronic kidney disease (CKD) and kidney failure, many individuals may have been able to avoid these severe and potentially life-threatening injuries. In addition to Nexium, other PPIs include Prilosec (omeprazole), Protonix (pantoprazole), Prevacid (lansoprazole), Dexilant (dexlansoprazole), Aciphex (rabeprazole) and their generic equivalents.

Mason is seeking a jury trial, punitive and compensatory damages, and litigation costs. The complaint was filed May 3 in the U.S. District Court for the Southern District of Illinois under case number 3:16-cv-00493.

Do I Have a Nexium Lawsuit?

The Pharmaceutical Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Nexium lawsuits. We are handling individual litigation nationwide and currently accepting new injury and death cases in all 50 states.

Free Confidential Case Evaluation: Again, if you’ve been injured by Nexium, you should contact our law firm immediately. You may be entitled to a settlement by filing a suit and we can help.

Nexium Kidney Failure Lawsuit

Nexium 20mg

The heartburn medication Nexium (esomeprazole magnesium) has been linked to an increased risk for nephritis (inflammation of the kidneys) and chronic kidney disease (CKD), conditions that can lead to kidney failure if left untreated.

Free Confidential Lawsuit Evaluation: If you suffered kidney failure or other damage to your kidneys after taking Nexium, you should contact our law firm immediately. You may be entitled to compensation by filing a suit against the manufacturer and our lawyers can help.

Update: Nexium Kidney Failure Lawsuit Filed in New York

September 14, 2016 – A man who claims he developed chronic kidney disease as a result of taking Nexium for approximately 7 years has filed a lawsuit against AstraZeneca in the U.S. District Court for the Eastern District of New York. Plaintiff George Mullen alleges that in addition to the kidney damage, he suffered other serious side effects which caused him physical pain, mental anguish, diminished quality of life, as well as monetary expenses resulting from ongoing medical treatment.

What is Nexium?

Since it was approved by the U.S. Food & Drug Administration (FDA) in September 2001, Nexium has become one of the most widely prescribed drugs in America, and generated about $6 billion in annual sales for AstraZeneca before it lost patent protection and became available as a generic.

Nexium is used to treat the symptoms of gastroesophageal reflux disease (GERD), heartburn, stomach ulcers and inflammation of the esophagus. It belongs to a class of drugs called proton pump inhibitors (PPI) which includes Prilosec (omeprazole), Prevacid (lansoprazole), Protonix (pantoprazole) and others.
AstraZeneca has aggressively marketed the “Purple Pill” as safe and effective; however, recent studies have found that users of the drug may face an increased risk of long-term kidney damage and even full-blown kidney failure.

PPIs Linked to Nephritis: FDA Warning

In December 2014, FDA announced new warnings to the labeling of Nexium and other PPI heartburn medications regarding a form of kidney damage called acute interstitial nephritis, which is characterized by a sudden inflammation of the kidneys that can lead to more severe problems.

Acute interstitial nephritis has been observed in patients taking PPIs including Nexium,” the warning states. “Acute interstitial nephritis may occur at any point during PPI therapy and is generally attributed to idiopathic hypersensitivity reaction. Discontinue Nexium if acute interstitial nephritis develops.”

Nexium Kidney Damage Studies

In April 2015, a study published in the medical journal CMAJ Open found that PPI users had a 2.5-fold increased risk of developing acute kidney injury, as well as a 3 times higher risk of acute interstitial nephritis compared to patients who did not take the drugs. The study’s authors highlighted the importance of doctors understanding the risk of these injuries, indicating that patients should be monitored and indiscriminate PPI use should be discouraged.

Another study published in JAMA Internal Medicine in January 2016 found that PPIs may significantly increase the risk of chronic kidney disease (CKD). The researchers looked at data on more than 10,000 participants in the the Atherosclerosis Risk in Communities Study (ARIC), and determined that PPI users had a 45% increased risk of CKD compared to non-users. When the figures were adjusted for demographics, socioeconomic and clinical variables, a 50% increased risk was detected. If left untreated, kidney disease and nephritis may lead to kidney failure (end-stage renal disease or ESRD), the need for life-long dialysis treatment or a kidney transplant.

Kidney Failure Symptoms

According to the American Kidney Fund, kidney failure is the last stage of CKD. When the kidneys fail, it means they have stopped functioning adequately enough for the patient to survive without dialysis or a kidney transplant. Signs and symptoms of kidney failure include:

  • Itching
  • Muscle cramps
  • Nausea / vomiting
  • Not feeling hungry
  • Swelling in the feet and/or ankles
  • Changes in urinary output
  • Breathlessness
  • Trouble sleeping

Treatment

Patients with ERSD will require dialysis or a kidney transplant to survive. There is no cure for kidney failure, but many people with the condition live long lives while undergoing dialysis or after having a kidney transplant. There are many options available to treat kidney failure, including kidney transplant and several types of dialysis. Your doctor can help you figure out which treatment option is best for you.

Indiana Man Alleges Kidney Failure from Nexium

May 9, 2016 – A man from Madison County, Illinois, who allegedly developed kidney failure after using Nexium has filed a class action lawsuit (PDF) against AstraZeneca. According to the lawsuit, plaintiff Harry Mason began taking Nexium in 2006, which ultimately led to his development of kidney failure requiring the need for a kidney transplant. The complaint is believed to be one of the first in what will likely be a steady stream of litigation alleging side effects from Nexium and other PPIs.

Proton Pump Inhibitors Linked to Kidney Disease, Study Finds

April 14, 2016 – Taking Nexium or other PPI heartburn medication may increase your risk of chronic kidney disease and renal failure, according to a study published today in the Journal of the American Society of Nephrology (JASN). The researchers found that those who take proton pump inhibitors are more likely than people who take histamine H2 receptor blockers (Pepcid, Tagamet, Zantac) to develop CKD or end-stage renal disease (ESRD) over a 5-year period.

Do I Have a Nexium Kidney Failure Lawsuit?

The Pharmaceutical Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Nexium lawsuits. We are handling individual litigation nationwide and currently accepting new kidney failure cases in all 50 states.

Free Confidential Case Evaluation: Again, if you or a loved one developed kidney failure from Nexium, you should contact our law firm immediately. You may be entitled to a settlement by filing a suit and we can help.

Nexium Bone Fracture Lawsuit

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AstraZeneca’s widely-prescribed heartburn medication Nexium (esomeprazole magnesium) has recently been linked to bone fractures and bone breaks, particularly among users who have taken the drug for a long period of time. In May 2010, the U.S. Food & Drug Administration (FDA) required that labels of Nexium and other proton pump inhibitors (PPIs) be updated to include information about this risk. Recent studies have also linked PPI heartburn medications to chronic kidney disease (CKD), renal failure and nephritis (inflammation of the kidneys).

Overview

First approved by the FDA in February 2001, Nexium is a proton pump inhibitor drug used to treat the symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid. It is AstraZeneca’s best-selling drug, as well as the third best-selling medication in the world, generating over $5.2 billion in sales in 2008 alone. Esomeprazole, the active ingredient in Nexium, is now manufactured by several companies under the brand names:

Nexium Bone Fractures

It has been theorized that Nexium has the potential to cause bone fractures because it reduces acid in the stomach, which in turn lowers the amount of calcium dissolved and absorbed into the body. Nexium also interferes with the body’s ability to break down and rebuild bone by manipulating the acid production of osteoclasts. Additionally, the reduction of B-12 by raising homocysteine may make the bones more fragile and prone to fractures or breaks.

FDA Warning on Nexium

The FDA’s review of several long-term studies which found an increased risk of hip, wrist, and spine fractures in PPIs users prompted the administration in May 2010 to revise labeling requirements for the drugs. The research indicated that these fractures occurred more often in patients who used PPIs like Nexium for more than one year at a higher dose. Then in 2011, researchers reiterated the fact that the risk of bone fractures greatly increased when using PPIs. Scientists found that PPI users who smoked had a 51% increased risk of suffering a hip fracture, and concluded that the longer the duration of use, the greater the risk of a fracture.

Nexium Bone Fracture Lawsuit Filed in Texas

In April 2011, a lawsuit was filed on behalf of an Ohio woman who suffered severe bone deterioration and broken bones after taking Nexium. Filed in the U.S. District Court in Houston, the complaint alleges that 58-year-old Ginny Begin suffered serious bone deterioration after taking Nexium on a daily basis from 2003 until early 2011.

PPI Heartburn Medications May Increase Risk of Kidney Disease, Study Finds

In addition to increasing the risk of bone fractures and breaks, Nexium and other PPIs may cause chronic kidney disease (CKD) and other kidney damage in some users. According to a Jan. 2016 study published in JAMA Internal Medicine, PPI users had a 45% increased risk of developing CKD compared to non-users.

 

U.K. Issues Proton Pump Inhibitor (PPI) Bone Fracture Warnings

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U.K. health regulators have issued two new warnings to the public stating that the use of proton pump inhibitor (PPI) heartburn drugs may cause bone fractures, and have the potential to lead to dangerously low levels of magnesium in the body. According to the warnings, these risks are increased if high doses of PPIs are taken over long periods of time, and appear to primarily affect the elderly. Heartburn drugs belonging to the PPI class include Nexium, Prilosec, Protonix, Prevacid, Aciphex, Dexilant, Vimovo and Zegerid.

What’s the problem?

April 25, 2012 – During the month of April, the United Kingdom’s Medicines and Healthcare Products Regulatory Agency (MHRA) issued two separate warnings regarding proton pump inhibitor heartburn medications. The first warning stated that new evidence indicates an increased risk of hip, spine and wrist fractures associated with PPI use. The MHRA advised patients taking the medications to be sure they are getting enough calcium and vitamin D in their diets to reduce the bone fracture risk.

The other warning involved severe cases of magnesium deficiency (also known as hypomagnesaemia) which have been increasingly linked to PPIs. According to the statement, magnesium deficiency is associated with long-term use of the drugs at high doses. This evidence came from a review of adverse event reports sent to health authorities across Europe. In severe cases, hypomagnesaemia can cause fatigue, delirium, convulsion, dizziness, and other serious side effects.

Proton pump inhibitors are designed to reduce the amount of acid in the stomach, and are generally prescribed to treat the following conditions:

  • gastroesophageal reflux disease (GERD)
  • heartburn
  • ulcers in the stomach and small intestines
  • inflammation of the esophagus

In May 2010, the U.S. Food & Drug Administration (FDA) issued a warning stating that there may be an increased risk of bone fractures from PPI heartburn medications. The warning was updated a year later with an indication that this risk was linked to high doses of the drugs taken over prolonged periods of time. According to the FDA, this risk does not apply to over-the-counter PPIs.

The consumer watchdog group Public Citizen has petitioned the FDA to require black box warnings to be added to PPI labels, alerting users that the drugs have been linked to bone fractures and can cause dependency in a relatively short period of time.

Over the past several years, a growing number of PPI bone fracture lawsuits have been filed in courthouses around the country. The claims allege that drugmakers failed to adequately research their drugs and neglected to warn the public about the risk of bone fractures.

Nexium & Prilosec Bone Fracture Lawsuit Filed Against AstraZeneca

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A lawsuit has been filed against AstraZeneca on behalf of a woman who allegedly suffered catastrophic foot fractures after taking Nexium (esomeprazole) and Prilosec (omeprazole).

Free Confidential Lawsuit Evaluation: If you or a loved one suffered kidney damage after taking Nexium or Prilosec, you should contact our law firm immediately. You may be entitled to compensation by filing a suit against the manufacturer and our lawyers can help.

Update: Studies Link PPIs to Kidney Problems

A pair of recent studies have linked proton pump inhibitor (PPI) heartburn medications like Nexium and Prilosec to severe, potentially life-threatening kidney problems:

What’s the problem?

July 14, 2011 – The new product liability claim, which was filed against AstraZeneca on behalf of Susan A. Poznavich in New Jersey Superior Court in Bergen County, alleges that the woman suffered a number of severe foot fractures after taking Nexium and Prilosec, popular heartburn drugs that have garnered extensive media coverage recently after being linked to an increased risk of bone problems.

Poznavich’s claim is just one of a growing number of lawsuits filed by Nexium and Prilosec users in recent months. In May 2011, a claim was filed on behalf of 35 people in Texas who allegedly suffered bone deterioration and fractures after taking Nexium. The lawsuit was filed in Harris County District Court against AstraZeneca and a Houston-area sales manager, claiming that despite having knowledge of the side effects associated with the drug, Nexium was marketed and sold to the public without adequate warnings for consumers. According to the suit, Nexium caused various injuries to the plaintiffs including fractures of the foot, ankle, leg, arm, hand, knee and vertebrae.

Proton Pump Inhibitors (PPIs)

Nexium (esomeprazole) and Prilosec (omeprazole) belong to a class of drugs known as proton pump inhibitors (PPIs), whose main action is a pronounced and long-lasting reduction of gastric acid production. PPIs are extremely popular and widely used, with doctors writing nearly 115 million prescriptions for the medications each year nationwide. Nexium is AstraZeneca’s best selling prescription drug, as well as the third best-selling medication in the world, with over $5.2 billion in sales in 2008 alone. In May 2010, the U.S. Food & Drug Administration (FDA) warned that there may be an increased risk of bone fractures from these drugs. In March 2011, the administration updated its Nexium bone fracture warning, highlighting the fact that the risk of broken bones appears to be linked to high doses of the drugs used over an extended period of time.

Side Effects of Nexium & Prilosec

Studies have shown that the use of PPI medications like Nexium and Prilosec may greatly increase the risk of a number of side effects including:

  • chronic kidney disease (CKD)
  • nephritis (inflammation of the kidneys)
  • renal failure (end-stage renal disease or ESRD)
  • bone fractures
  • abdominal pain
  • constipation
  • nausea
  • diarrhea
  • stroke
  • allergic reactions
  • heart attack
  • weight loss
  • erectile dysfunction (ED)

Nexium & Prilosec FDA Warning

In May 2010, the FDA issued a press release stating that it was requiring the labels of PPI drugs like Nexium and Prilosec to be revised. The press release informed the public that PPIs may increase the risk of wrist, hip and spine fractures. In the announcement, the FDA advised users and doctors to weigh the benefits vs. risks of these medications closely before beginning a regimen.

Do I have a Nexium Lawsuit?

The Pharmaceutical Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Nexium and Prilosec lawsuits. We are handling individual litigation nationwide and currently accepting new kidney failure cases in all 50 states.

Free Confidential Case Evaluation: Again, if you suffered kidney damage after taking Nexium or Prilosec, you should contact our law firm immediately. You may be entitled to a settlement by filing a suit and we can help.