Cipla Pharmaceuticals’ popular cholesterol-lowering drug Simlup has recently been linked to a number of serious side effects including muscle damage, myopathy, and kidney failure. Recent studies have indicated that the risk of Simlup-induced complications is directly proportional to the dose taken, so patients taking higher dosages of the drug are at an increased risk of side effects compared to those on lower dose regimens. The Simlup Lawyers at Schmidt & Clark, LLP, are currently offering free, no-obligation consultations to individuals injured by Simlup side effects.
Free Simlup Lawsuit Evaluation: If you suffered one or more of the injuries listed in this article after taking Simlup, or if a loved one died while being treated with the drug, you should contact our law firm immediately. You may be entitled to compensation by filing a suit against the manufacturer of Simlup and we can help.
Manufactured and marketed by Cipla Pharmaceuticals, Simlup (generic: simvastatin) belongs to a class of medications known as HMG CoA reductase inhibitors, or ‘statins.’ Drugs from this class are designed to reduce levels of ‘bad’ cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while simultaneously increasing levels of ‘good‘ cholesterol (high-density lipoprotein, or HDL). In addition to being used for these purposes, Simlup is also commonly used to lower the risk of stroke, heart attack, or other heart-related complications in patients with diabetes, coronary heart disease, and other risk factors.
Simlup Side Effects
Despite being a considerably effective cholesterol-lowering medication, Simlup has been increasingly linked to a number of severe, potentially life-threatening side effects. Individuals taking the 80 mg dose of Simlup are at risk of developing the following complications:
- muscle damage
- kidney damage
- kidney failure
Simlup Myopathy & Rhabdomyolysis
High doses of Simlup and other statin drugs have been linked to myopathy, a condition in which the patient experiences severe muscle pain and tenderness. The degree of myopathy a patient experiences depends on the dose of the drug taken, meaning that those who take higher doses face a significantly increased risk of developing the condition compared to those taking lower doses. In extreme cases of myopathy, the muscle cells break down and lead to a condition known as rhabdomyolysis, which is characterized by a release of myoglobin into the patient’s bloodstream. If left untreated, rhabdomyolysis can cause damage to the kidneys, as the kidneys attempt to filter the protien out of the bloodstream. Signs and symptoms of Simlup-induced rhabdomyolysis may include:
- muscle pain
- tenderness, weakness or swelling of the affected muscles
- low blood pressure
- abnormal heart rate and rhythm
Simlup & Kidney Failure
When caused by Simlup or other statin drug, kidney failure is often the direct result of myopathy. During the process of myopathy, the dead muscle fibers release myoglobin into the bloodstream which may harm the kidneys and ultimately lead to acute kidney failure. This condition is characterized by the sudden inability of the kidneys to remove waste and concentrate urine. Signs and symptoms may include:
- weight loss
- nocturnal urination
- more or less frequent urination habits
- bone damage
- muscle cramps
- abnormal heart rhythms
- muscle paralysis
- swelling of the legs, ankles, feet or hands
- low blood pressure
Simlup kidney failure is a serious, potentially life-threatening condition that typically requires emergency medical intervention. If treatment is neglected, the chances of a patient surviving Simlup kidney failure may be significantly decreased. Due to the severity of the disease, many patients have filed a Simlup lawsuit against Cipla Pharmaceuticals.
FDA Warning on Simlup
In June 2011, the U.S. Food & Drug Administration (FDA) issued a nationwide simvastatin warning which stated that patients who took the highest dose of the drug (80 mg) were at risk of developing muscle injury (myopathy), especially within the first year of beginning a regimen. The FDA advised doctors not to start any new patients on 80 mg of simvastatin, and recommended that patients currently taking the maximum dose should only continue to do so if they have used the drug for at least a year without experiencing muscle pain. In addition to Simlup, the FDA warning applied to all medications containing simvastatin, including Zocor, Simcard, and Simvacor.
Do I Have a Simlup Lawsuit?
The Product Liability & Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Simlup lawsuits. We are handling individual litigation nationwide and currently accepting new Simlup injury and death cases in all 50 states.
Free Simlup Lawsuit Evaluation: If you suffered one or more of the injuries listed in this article after taking Simlup, or if a loved one died while being treated with the drug, you should contact our law firm immediately. You may be entitled to compensation by filing a Simlup suit and we can help.