A new study has found that glyphosate — the main ingredient in Roundup weedkiller — alters DNA function, increasing the risk for a number of serious, potentially life-threatening diseases.
Free Confidential Lawsuit Evaluation: If you or a loved one was diagnosed with any form of non-Hodgkins lymphoma after using or being exposed to Roundup, you should contact our law firm immediately. You may be entitled to compensation by filing a suit and our lawyers can help.
What’s the Problem?
July 19, 2016 – According to the study, entitled “Glyphosate pathways to modern diseases V: Amino acid analogue of glycine in diverse proteins”, glyphosate acts as a glycine analogue that incorporates into peptides during protein synthesis. When this occurs, the herbicide changes proteins that depend on conserved glycine to function.
According to the study, glyphosate substitution for glycine is associated with a number of serious diseases including (but not limited to):
- Type 2 diabetes
- Alzheimer’s disease
- Amyotrophic lateral sclerosis (ALS)
- Parkinson’s disease
Glycine, the smallest of the 20 amino acids found in proteins, has unique properties that have the ability to anchor to the plasma membrane or cytoskeleton. The new study, taken in conjunction with with correlating data, makes a compelling argument that glyphosate action as a glycine analogue accounts for a high percentage of glyphosate’s toxicity.
Additionally, the researchers found that the herbicide may be incorporated into polypeptide chains during protein synthesis, which affects the structure and function of the proteins. Proteins fold up, and glycine is a tiny molecule that is often found in the folding spaces. Since glyphosate is much larger, it prevents the protein molecule from folding correctly, disrupting the function of proteins involved with metabolism and regulatory processes, according to the study.
This mechanism affects humans and other organisms in a number of ways including:
- Impaired fatty acid release leading to obesity;
- Impaired insulin receptor response leading to type 2 diabetes;
- Impaired one-carbon metabolism leading to neural tube defects and autism;
- Impaired cell cycle control during DNA synthesis, and
- Dysregulated phosphorylation cascades leading to cancer, lung disorders and autoimmune diseases.
“When a cell is trying to form proteins, it may grab glyphosate instead of glycine to form a damaged, mis-folded protein,” said Stephen Frantz, Ph.D., a pathobiologist research scientist. “After that it’s medical chaos. Where glyphosate replaces glycine, the cell can no longer conduct business as usual causing unpredicted consequences with many diseases and disorders as a result.”
Monsanto touts glyphosate as a “low toxicity” herbicide and “safer” than other weedkillers. However, the chemical has also been shown to have negative effects on humans and the environment. Given its massive use on residential and agricultural sites, its toxicity is of growing concern.
Last year, the World Health Organization’s (WHO) International Agency for Research on Cancer (IARC) classified glyphosate as a “probable human carcinogen.” In February 2016, a study published in Environmental Health News determined that chronic, low-dose exposure to glyphosate could cause adverse effects on liver and kidney health.
Do I Have a Roundup Lawsuit?
The Workplace and Environmental Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Roundup herbicide lawsuits. We are handling individual litigation nationwide and currently accepting new injury and death cases in all 50 states.
Free Confidential Case Evaluation: Again, if you developed any form of non-Hodgkins lymphoma (NHL) after using or being exposed to Roundup, you should contact our law firm immediately. You may be entitled to a settlement by filing a suit and we can help.