Recent studies have found that Janssen Pharmaceuticals’ popular antipsychotic drug Risperdal may cause a stroke in some patients. This risk is significantly increased in elderly patients suffering from dementia. Sadly, Risperdal has been linked to dozens of strokes and at least 16 deaths since it first hit the market.
Free Risperdal Stroke Lawsuit Evaluation: If you or a loved one had a stroke after taking Risperdal, you should contact our law firm immediately. You may be entitled to compensation by filing a suit against the manufacturer of Risperdal and we can help.
Although no antipsychotic drug has been approved by the U.S. Food & Drug Administration (FDA) for the treatment of behavioral disturbance in dementia, they are commonly prescribed ‘off-label’ for this purpose. In the U.K., the Committee on Safety of Medicines (CSM) recently examined the available data from trials on Risperdal and olanzapine (another atypical antipsychotic in the same class as Risperdal).
Risperidone (the main active ingredient contained in Risperdal) is the most exhaustively studied drug in this context and a meta-analysis of trials in elderly people suffering from dementia has indicated that, when compared to a placebo, the risk of stroke with Risperdal was increased approximately threefold. An analysis of randomized trials of olanzapine in elderly patients with dementia has found a similar risk of stroke, and a nearly twofold increase in all-cause mortality.
The specific mechanisms by which risperidone and olanzapine cause strokes are still not clearly understood. Although some people suffering from dementia may have underlying vascular disease, the risk of stroke is not limited to this group. Although the vast majority of the evidence comes from dementia patients, the stroke risk may not be limited to Risperdal use for this purpose, and should be considered relevant to any user with a history of cerebrovascular disease.
Risks & Benefits of Risperdal
CSM has determined that there is evidence of an increased risk of stroke in elderly people with dementia who use risperidone or olanzapine. The severity of this risk is enough to outweigh the potential benefits in treating behavioral disturbances caused by dementia, and is reason for concern in any patient with stroke risk factors.
CSM recommends these prescribing restrictions for Risperdal:
- Risperidone should not be prescribed for the treatment of behavioral symptoms associated with dementia.
- Prescribing Risperdal to manage psychotic conditions in elderly individuals who also have dementia should be limited to short-term use.
- Prescribing doctors should consider the risk of cerebrovascular side effects before treating any patient with a history of stroke or transient ischaemic attack. Consideration should also be given to other risk factors including hypertension, type 2 diabetes, cigarette smoking and atrial fibrillation.
- Risperdal users with dementia should have their treatment periodically reviewed by a doctor. Many dementia patients may be treated without prescription medications.
Do I Have a Risperdal Stroke Lawsuit?
The Product Liability & Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Risperdal Lawsuits. We are handling individual litigation nationwide and currently accepting new Risperdal Stroke Cases in all 50 states.
Free Risperdal Stroke Lawsuit Evaluation: If you or a loved one had a stroke after taking Risperdal, you should contact our law firm immediately. You may be entitled to compensation by filing a Risperdal Stroke Suit and we can help.