Reglan Side Effects and Withdrawal Symptoms
Reglan Side Effects: an Overview
Reglan (one of the trade names for a drug called metoclopramide) is classified as a dopamine antagonist. In order to understand how the side effects of this drug work, it is helpful to know something about how the brain and nervous system work together in order to control bodily functions and the role of dopamine.
In order for the human body to act on instructions from the brain, it is necessary for them to be translated into a form that the cells can understand. Just as a personal computer has a modem in order to translate electrical data into information the browser can read, so too do your cells have dopamine receptors which receive and translate instructions from the brain.
Metoclopramide was initially developed for this purpose, but was found to be less effective than many other antipsychotic drugs in use. A study published in 2004 found that like many other dopamine antagonists, metoclopramide could cause a movement disorder known as Tardive Dyskinesia. This ultimately led to action by the FDA, which required a black box warning on all packages of Reglan.
Reglan Side Effects
The following is a list of symptoms associated with Reglan side effects:
- Severe allergic reactions (rash, hives, itching, difficulty breathing, tightness in the chest, swelling of the mouth, face, lips or tongue)
- Abnormal thinking
- dark urine
- Decreased balance or coordination
- Decreased sexual ability
- Fast, slow, or irregular heart beat
- Loss of bladder control
- Mental or mood changes (depression, anxiety, agitation, jitteriness)
- Severe or persistent dizziness
- Trouble sleeping
- Severe or persistent restlessness
- Stiff or rigid muscles
- Sudden increased sweating
- Unusual weight gain
- Suicidal thoughts or actions