Onglyza (generic: saxagliptin) belongs to a group of type 2 diabetes medications that have been linked to reports of pancreatitis, pancreatic cancer and thyroid cancer.
Free Confidential Case Evaluation: If you or a loved one was diagnosed with pancreatic cancer after taking Onglyza, you should contact our law firm immediately. You may be entitled to compensation by filing a suit against the manufacturer and and our lawyers can help.
What’s the Problem?
Onglyza was approved by the U.S. Food & Drug Administration (FDA) in July 2009 for the treatment of type 2 diabetes. The medication is classified as an incretin mimetic, which lowers blood sugar levels by mimicking a metabolic hormone (“incretin”) called GLP-1 that stimulates the proliferation of cells in the pancreas which produce insulin. Unfortunately, this mechanism of action may increase a user’s risk of developing pancreatitis, pancreatic cancer and/or thyroid cancer.
Onglyza Pancreatic Cancer
In March 2013, FDA issued a Drug Safety Communication regarding a potential link between incretin mimetic diabetes drugs and damage to the pancreas:
“The U.S. Food and Drug Administration (FDA) is evaluating unpublished new findings by a group of academic researchers that suggest an increased risk of pancreatitis, or inflammation of the pancreas, and pre-cancerous cellular changes called pancreatic duct metaplasia in patients with type 2 diabetes treated with a class of drugs called incretin mimetics.”
While earlier studies suggested that incretin mimetics may be linked to pancreatitis, the FDA warning raises the possibility that these medications may be associated with pancreatic cancer.
Pancreatic Cancer Symptoms
- Upper abdominal pain
- Weight loss
- Jaundice (yellowing of the skin and whites of the eyes)
- Severe itching
- Nausea and vomiting
- Digestive problems
FDA has received dozens of reports of thyroid cancer in diabetes patients treated with the incretin mimetics Byetta (exenatide), Januvia (sitagliptin) and Victoza (liraglutide). In 2009, the agency asked Amylin Pharmaceuticals to explore the potential link between Byetta and cancers of the pancreas and thyroid gland. Two years later, a study published in the medical journal Gastroenterology (PDF) found dozens of cases of thyroid cancer in patients treated with Byetta and Januvia.
Symptoms of Thyroid Cancer
- Lump in the neck
- Swelling in the neck
- Pain in the front of the neck
- Hoarseness or other voice changes that do not go away
- Trouble swallowing
- Trouble breathing
Incretin Mimetic Drug List
In addition to Onglyza, other incretin mimetic diabetes medications that may increase the risk of cancer include:
- Byetta (exenatide)
- Bydureon (exenatide)
- Janumet (metformin and sitagliptin)
- Janumet XR (sitagliptin and metformin HCl extended-release)
- Januvia (sitagliptin)
- Jentadueto (linagliptin and metformin)
- Kazano (alogliptin and metformin)
- Kombiglyze XR (saxagliptin and metformin)
- Nesina (alogliptin)
- Oseni (alogliptin and pioglitazone)
- Tradjenta (linagliptin)
- Victoza (liraglutide)
Has There Been a Recall?
Despite being linked to reports of pancreatitis, pancreatic cancer and thyroid cancer, neither Onglyza nor any other incretin mimetic has been recalled in the U.S. or any other country. However, despite the lack of a recall, diabetes patients who developed pancreatic cancer after taking these drugs may be able to file a product liability claim against the manufacturer. If our lawyers determine that you have a valid claim, you may be eligible to receive compensation for medical bills, lost wages, pain and suffering, and other damages.
Do I Have an Onglyza Cancer Lawsuit?
The Product Liability & Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Onglyza Lawsuits. We are handling individual litigation nationwide and currently investigating potential settlements in all 50 states.
Free Confidential Case Evaluation: Again, if you or a loved one was injured by Onglyza side effects, you should contact our law firm immediately. You may be entitled to compensation by filing a class action suit and we can help.