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Nexium Side Effects | Risks, Interactions & More

Recent studies have linked the popular heartburn drug Nexium (generic: esomeprazole) to serious side effects including chronic kidney disease (CKD), interstitial nephritis, heart attack, bone fractures and more.
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If you or a loved one experienced a serious injury from Nexium, you should contact an attorney immediately.

You may be entitled to compensation by filing a lawsuit and an attorney can help. Please click the button below for a Free Case Evaluation or call us toll-free 24 hrs/day by dialing (866) 588-0600.

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Does Nexium Have Long-Term Side Effects?

Taking esomeprazole, the active ingredient in Nexium, for more than 14 days at a time may cause you to develop the following serious side effects:

  • Acute interstitial nephritis (inflammation of the kidneys)
  • Acute kidney injury
  • Chronic kidney disease (CKD)
  • Kidney failure
  • Cardiovascular diseases
  • Heart attack
  • Ischemic Stroke Risk
  • Gastric tumors, bone fractures (hip fracture, wrist fracture, spine fracture) and anemia
  • Broken bones
  • Low magnesium levels (hypomagnesemia)
  • Stomach cancer
  • Gut infections
  • Clostridium difficile-associated diarrhea
  • Community-acquired pneumonia
  • Risk of dementia
  • Erectile dysfunction (ED)
  • Severe allergic reactions

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What Does Nexium Do To Your Stomach?

Nexium works by decreasing the amount of acid in your stomach. The drug is designed to relieve symptoms of heartburn, gastroesophageal reflux disease (GERD), difficulty swallowing, and persistent cough. Nexium helps heal acid damage to the stomach and esophagus, and helps prevent ulcers.

Why Was Nexium Taken Off the Market?

In January 2020, the U.S. Food and Drug Administration (FDA) announced that a number of popular antacids -- Zantac and its generic version, ranitidine, as well as nizatidine (Tezac, Axid) -- were being recalled after they were found to contain "unacceptable" amounts of N-Nitrosodimethylamine (NDMA), a substance the World Health Organization has classified as a "probable human carcinogen."

Nexium and other heartburn medications including famotidine (Pepcid), cimetidine (Tagamet), lansoprazole (Prevacid) and omeprazole (Prilosec) did not test positive for NDMA contamination and were not removed from the market.

Is it OK to Take Nexium Every Day?

You should not take more than one Nexium capsule per day. Do not chew the capsule or empty its contents into food or drink.

Do not take Nexium for more than 14 days unless your doctor tells you to. You can repeat a 14-day regimen once every 4 months.

What Should I Not Take With Nexium?

Nexium may interact with certain medications or supplements, including:
  • Cilostazol
  • Clopidogrel
  • Methotrexate (especially high-dose treatment)
  • Rifampin
  • St John's wort

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The Pharmaceutical Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in lawsuits against Nexium.

We are handling individual litigation nationwide and currently investigating potential class action lawsuits in all 50 states.

Again, if you were injured by Nexium, you should contact our law firm immediately for a free case evaluation. You may be entitled to a settlement by filing a Nexium Kidney lawsuit and a Lawyer can help.

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