Free Confidential Lawsuit Evaluation: If you or a loved one suffered kidney damage after taking Nexium or Prilosec, you should contact our law firm immediately. You may be entitled to compensation by filing a suit against the manufacturer and our lawyers can help.
Update: Studies Link PPIs to Kidney Problems
A pair of recent studies have linked proton pump inhibitor (PPI) heartburn medications like Nexium and Prilosec to severe, potentially life-threatening kidney problems:
- A January 2016 study published in JAMA Internal Medicine found that PPIs may significantly increase the risk of chronic kidney disease (CKD). The researchers looked at data on more than 10,000 participants in the Atherosclerosis Risk in Communities (ARIC) study, and determined that PPI users had a 45% increased risk of developing CKD compared to patients who did not take the medications. When the figures were adjusted for variables, a 50% increased risk was detected.
- Another study published in the Journal of the American Society of Nephrology (JSAN) in April 2016 found that long-term PPI use increased the risk of CKD by 28% compared PPIs to histamine H2 receptor blockers (Pepcid, Tagamet, Zantac). Only a few patients in the study (>0.2%) developed end-stage renal disease (ESRD), but the risk was 96% higher for those on PPIs.
What’s the problem?
July 14, 2011 – The new product liability claim, which was filed against AstraZeneca on behalf of Susan A. Poznavich in New Jersey Superior Court in Bergen County, alleges that the woman suffered a number of severe foot fractures after taking Nexium and Prilosec, popular heartburn drugs that have garnered extensive media coverage recently after being linked to an increased risk of bone problems.
Poznavich’s claim is just one of a growing number of lawsuits filed by Nexium and Prilosec users in recent months. In May 2011, a claim was filed on behalf of 35 people in Texas who allegedly suffered bone deterioration and fractures after taking Nexium. The lawsuit was filed in Harris County District Court against AstraZeneca and a Houston-area sales manager, claiming that despite having knowledge of the side effects associated with the drug, Nexium was marketed and sold to the public without adequate warnings for consumers. According to the suit, Nexium caused various injuries to the plaintiffs including fractures of the foot, ankle, leg, arm, hand, knee and vertebrae.
Proton Pump Inhibitors (PPIs)
Nexium (esomeprazole) and Prilosec (omeprazole) belong to a class of drugs known as proton pump inhibitors (PPIs), whose main action is a pronounced and long-lasting reduction of gastric acid production. PPIs are extremely popular and widely used, with doctors writing nearly 115 million prescriptions for the medications each year nationwide. Nexium is AstraZeneca’s best selling prescription drug, as well as the third best-selling medication in the world, with over $5.2 billion in sales in 2008 alone. In May 2010, the U.S. Food & Drug Administration (FDA) warned that there may be an increased risk of bone fractures from these drugs. In March 2011, the administration updated its Nexium bone fracture warning, highlighting the fact that the risk of broken bones appears to be linked to high doses of the drugs used over an extended period of time.
Side Effects of Nexium & Prilosec
Studies have shown that the use of PPI medications like Nexium and Prilosec may greatly increase the risk of a number of side effects including:
- chronic kidney disease (CKD)
- nephritis (inflammation of the kidneys)
- renal failure (end-stage renal disease or ESRD)
- bone fractures
- abdominal pain
- allergic reactions
- heart attack
- weight loss
- erectile dysfunction (ED)
Nexium & Prilosec FDA Warning
In May 2010, the FDA issued a press release stating that it was requiring the labels of PPI drugs like Nexium and Prilosec to be revised. The press release informed the public that PPIs may increase the risk of wrist, hip and spine fractures. In the announcement, the FDA advised users and doctors to weigh the benefits vs. risks of these medications closely before beginning a regimen.
Do I have a Nexium Lawsuit?
The Pharmaceutical Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Nexium and Prilosec lawsuits. We are handling individual litigation nationwide and currently accepting new kidney failure cases in all 50 states.
Free Confidential Case Evaluation: Again, if you suffered kidney damage after taking Nexium or Prilosec, you should contact our law firm immediately. You may be entitled to a settlement by filing a suit and we can help.