You may be entitled to obtain compensation for medical bills by filing a Naprosyn Stevens-Johnson Syndrome Lawsuit and our lawyers can help. Please click the button below for a Free Case Evaluation or call us for a free legal consultation 24 hrs/day by dialing (866) 588-0600.
What is Naprosyn?
Naprosyn is a non-steroidal anti-inflammatory drug (NSAID) that is used to relieve pain from various conditions such as headaches, muscle aches, tendonitis, dental pain, and menstrual cramps. The drug works by blocking the effect of chemicals in the body called cyclo-oxygenase (COX) enzymes, which make other chemicals called prostaglandins. Some prostaglandins are produced at sites of injury or damage and cause pain and inflammation.
Naprosyn is manufactured and marketed by Bayer HealthCare and was approved by the U.S. Food and Drug Administration (FDA) on February 17, 2006.
What's the Problem?
More than 100 drugs can cause Stevens-Johnson syndrome / Toxic Epidermal Necrolysis, and NSAID pain relievers like Naprosyn are among the medications most commonly associated with the conditions. SJS / TEN are most likely to occur in the first 2 months of taking the offending medication.
Stevens-Johnson Syndrome Symptoms
In patients with SJS/TEN, flu-like symptoms appear first. A painful rash that spreads and blisters follows.
Medication Use and the Risk of SJS/TEN: Study
A study published in the New England Journal of Medicine in December 1995 [1.] was conducted to assess the risk of SJS/TEN associated with the use of specific medications. Drug use before the onset of the disease was compared in 245 people who were hospitalized due to SJS/TEN and 1147 patients hospitalized for other reasons (controls).
Among drugs used for short durations, the risks of SJS/TEN were increased for:
- Trimethoprim-sulfamethoxazole and other sulfonamide antibiotics (crude relative risk, 172; 95 percent confidence interval, 75 to 396)
- Chlormezanone (crude relative risk, 62; 21 to 188)
- Aminopenicillins (multivariate relative risk, 6.7; 2.5 to 18)
- Quinolones (multivariate relative risk, 10; 2.6 to 38)
- Cephalosporins (multivariate relative risk, 14; 3.2 to 59)
- Acetaminophen, the multivariate relative risk was 0.6 (95 percent confidence interval, 0.2 to 1.3) in France but 9.3 (3.9 to 22) in the other countries.
Among drugs used for months or years, the increased risk was confined largely to the first two months of treatment, when crude relative risks were as follows:
- Carbamazepine, 90 (95 percent confidence interval, 19 too ∞)
- Phenobarbital, 45 (19 to 108)
- Phenytoin, 53 (11 to ∞)
- Valproic acid, 25 (4.3 to ∞)
- Oxicam nonsteroidal anti-inflammatory drugs (NSAIDs), 72 (25 to 209)
- Allopurinol, 52 (16 to 167)
- Corticosteroids, 54 (23 to 124)
"The use of antibacterial sulfonamides, anticonvulsant agents, oxicam NSAIDs, allopurinol, chlormezanone, and corticosteroids is associated with large increases in the risk of Stevens–Johnson syndrome or toxic epidermal necrolysis," the researchers concluded.
Related Article: Stevens-Johnson Syndrome Lawsuit Update
What is the Recommended Treatment for Stevens-Johnson Syndrome?
Antibiotics to control infection may be used to treat SJS/TEN. Other oral or injected medications, such as corticosteroids and intravenous immune globulin may be implemented. Studies show that the drugs cyclosporine (Neoral, Sandimmune) and etanercept (Enbrel) are also helpful to treat the diseases.
SJS/TEN Risk Factors
You're more likely to develop SJS/TEN if you have:
- HIV or other immune system conditions
- Had SJS/TEN previously
- Certain inherited genes
- Radiation treatments
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See all related dangerous drug lawsuits our attorneys covered so far.
Get a Free Naprosyn Stevens-Johnson Syndrome Lawsuit Evaluation With Our Lawyers
The Pharmaceutical Litigation Group at Schmidt & Clark, LLP law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Naprosyn Stevens-Johnson Syndrome lawsuits. We are handling individual litigation nationwide and currently investigating potential settlements in all 50 states.
Again, if you or a loved one was diagnosed with Stevens-Johnson Syndrome (SJS) or Toxic Epidermal Necrolysis (TEN) after taking Naprosyn, you should contact our law firm immediately for a free case review. You may be entitled to compensation by filing a suit for legal fees and our defective drug lawyers can help with a free case evaluation.
