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Janumet Pancreatitis Causes

Although there is still much debate as to exactly how Janumet causes pancreatitis, the condition occurs when pancreatic enzymes become active in the pancreas and attack it. Pancreatitis is a serious disease that can lead to pancreatic cancer if not treated in a timely manner.

Janumet users around the country have been diagnosed with pancreatitis over the past several years. Although there is still much debate as to exactly how Janumet causes pancreatitis, the condition occurs when pancreatic enzymes become active in the pancreas and attack it. Janumet pancreatitis is a serious disease that can lead to full-blown pancreatic cancer if not treated in a timely manner.

Free Confidential Case Evaluation: If you or a loved one has been diagnosed with pancreatic cancer after taking Janumet, you should contact our law firm immediately. You may be entitled to compensation by filing a suit against the manufacturer of Janumet and we can help.

How Does Janumet Cause Pancreatitis?

Although the exact mechanisms of what causes Janumet pancreatitis are still not fully understood by the medical community, the disease is thought to begin when digestive enzymes in the pancreas become active while still inside the organ. Normally, pancreatic enzymes stay inert until they reach the small intestine, where they activate and aid in digestive processes. In people diagnosed with Janumet pancreatitis, the enzymes activate prematurely while still in the pancreas, causing sudden inflammation and other complications. If Janumet pancreatitis occurs repeatedly or over a long period of time, damage to the organ can lead to chronic pancreatitis, where scar tissue forms and causes the organ to malfunction. A damaged pancreas can cause digestion problems, diabetes, and other serious issues.

First approved by the U.S. Food & Drug Administration (FDA) in 2007, Janumet (metformin and sitagliptin) is a widely-prescribed type 2 diabetes drug that helps the pancreas produce insulin more efficiently. Janumet belongs to a controversial class of diabetes medications known as dipeptidyl peptidase-4 (DPP-4) inhibitors which include Byetta and Januvia. Despite showing early promise in combatting the symptoms of diabetes, Janumet and other DPP-4 inhibitors have been linked to pancreatitis, pancreatic cancer, and thyroid cancer.

Acute Hemorrhagic Pancreatitis

Janumet has been associated with acute hemorrhagic pancreatitis, a disease that occurs when the pancreas becomes inflamed over a short period of time. Patients with acute hemorrhagic pancreatitis experience symptoms such as confusion, breathing troubles, respiratory issues, and other complications. In severe cases of acute hemorrhagic pancreatitis, the patient may lapse into a coma. Warning signs of the disease may include:

  • Upper abdominal pain that radiates into the back
  • Swollen and tender abdomen
  • Nausea and vomiting
  • Fever
  • Increased heart rate

Necrotizing Pancreatitis

Janumet has also been linked to necrotizing pancreatitis, a life-threatening disease that occurs when a person’s pancreas is inflamed and bleeding. In patients suffering from necrotizing pancreatitis, the pancreas destroys itself, which causes inflammation and tissue death. This form of pancreatitis is severe and requires emergency medical treatment.

Do I Have a Janumet Lawsuit?

The Product Liability & Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Janumet lawsuits. We are handling individual litigation nationwide and currently accepting new Janumet pancreatic cancer cases in all 50 states.

Free Janumet Lawsuit Evaluation: If you or a loved one has been diagnosed with pancreatic cancer after taking Janumet, you should contact our law firm immediately. You may be entitled to compensation by filing a Janumet suit and we can help.

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