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How Long Does Nexium Stay In Your System?
What You Need to Know

The popular heartburn medication Nexium (generic: omeprazole) stays in your system longer than any other proton pump inhibitor, with a half-life of nearly three hours. A half-life is a measure of how long a drug stays active before the body eliminates it as waste.
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How Long Does Nexium Last?

PPIs like Nexium treat frequent heartburn by blocking the production of stomach acid. The drug may take 1-4 days to take full effect, but relief lasts for 24 hours.

What Happens When You Stop Taking Nexium?

You should not stop taking Nexium or any other prescription medication without talking to your doctor first. Quitting Nexium abruptly may lead to withdrawal symptoms and could make your stomach problems worse. Many Nexium side effects are mild and may go away after your body gets acclimated to the drug.

How Long Do Side Effects Last After Quitting Nexium?

When you discontinue treatment with Nexium, there is rebound gastric hyper-secretion in patients who have been on the medication for a long time. Rebound symptoms should resolve within two weeks.

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What Should I Eat When Coming off Nexium?

In addition to avoiding the foods that generally cause you heartburn, you might want to experiment with a low-carb diet when weaning yourself off Nexium. A 2006 study published in Digestive Diseases and Sciences [1] found that when obese individuals followed a very low-carb diet, their reflux symptoms improved and they had less acid splashing up into the lower part of the esophagus.

What Are the Symptoms of PPI Withdrawal?

Quitting treatment with a proton pump inhibitor cold turkey can lead to rebound acid hypersecretion, causing transient symptoms such as indigestion, heartburn, or regurgitation.

How Do I Stop Acid Rebound?

Slowly lowering the dose of Nexium before stopping it can help stop the acid rebound. Lowering your dose over a few weeks can help minimize acid rebound symptoms. Always consult your physician before lowering your dose of Nexium.

What are PPI Alternatives?

If you are looking to stop taking Nexium or another proton pump inhibitor, there are a variety of options you can use to treat your heartburn or acid reflux. These include histamine blockers, antacids, probiotics and lifestyle changes. In some cases, surgery is an option.

Related Article: Proton Pump Inhibitor (PPI) Lawsuit

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Again, if you were injured by Nexium, you should contact our law firm immediately for a free case evaluation. You may be entitled to a settlement by filing a lawsuit and a Lawyer can help.

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