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Study Links Common Heartburn Drugs to Increased Stroke Risk

A popular class of heartburn medications that includes Nexium and Prilosec may increase your risk of stroke, according to a new study.

A popular class of heartburn medications that includes Nexium (esomeprazole) and Prilosec (omeprazole) may increase your risk of stroke, according to a new study.

Free Confidential Lawsuit Evaluation: If you or a loved one suffered kidney damage after taking a proton pump inhibitor, you should contact our law firm immediately. You may be entitled to compensation by filing a suit and our lawyers can help.

What’s the Problem?

November 16, 2016 – The results of the study found that proton pump inhibitors (PPIs) increased a user’s overall risk of stroke by 21%. However, this risk appears to be largely driven by patients who take high doses of the medications.

“People treated with a low dose of PPIs did not have a high risk of stroke,” said Dr. Thomas Sehested, research director at the Danish Heart Foundation in Copenhagen and lead author of the study. “Those treated with the highest doses of PPIs had the highest risk of stroke.”

The extent of the risk also depends on the specific proton pump inhibitor taken. At the highest dose, stroke risk ranged from 30% with Prevacid (lansoprazole) to 94% with Protonix (pantoprazole), according to the study.

The researchers found that proton pump inhibitors increased the risk of ischemic stroke, the most common type of stroke that occurs when a blood clot blocks the flow of blood to the brain. PPIs treat heartburn by blocking acid-producing cells in the stomach.

For the study, researchers looked at the records of nearly 245,000 Danish patients who took PPIs to manage symptoms of gastroesophageal reflux disease (GERD). All had undergone an endoscopy, a medical procedure used to identify the causes of stomach pain and indigestion.

During 6 years of follow-up, nearly 9,500 patients in the cohort had their first ischemic stroke. Researchers checked to see if the stroke occurred while patients were taking any of the following proton pump inhibitors: Prilosec (omeprazole), Nexium (esomeprazole), Prevacid or Protonix. Researchers also asked about another class of antacids known as H2 blockers, which include Pepcid (famotidine) and Zantac (ranitidine).

The study found increased stroke risk with PPIs, but not with H2 blockers. Results were presented Tuesday at the American Heart Association (AHA) annual meeting in New Orleans.

Do I have a Proton Pump Inhibitor Lawsuit?

The Pharmaceutical Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in PPI lawsuits. We are handling individual litigation nationwide and currently accepting new kidney disease cases in all 50 states.

Free Case Evaluation: Again, if you were injured by the side effects of a heartburn medication, you should contact our law firm immediately. You may be entitled to a settlement by filing a suit and we can help.

Free Confidential Case Evaluation

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