People who take proton pump inhibitors (PPIs) for heartburn, indigestion and acid reflux may have an increased risk of developing kidney disease, according to a new study published in JAMA Internal Medicine.
Free Confidential Lawsuit Evaluation: If you or a loved one suffered kidney damage after using a heartburn medication, you should contact our law firm immediately. You may be entitled to compensation by filing a suit and our lawyers can help.
What’s the problem?
Proton pump inhibitors appear to significantly increase users’ risk of developing chronic kidney disease, according to the study, which involved more than 250,000 test subjects. The medications are taken by an estimated 15 million Americans, which are sold by prescription and over-the-counter (OTC) under the following brand names:
When PPIs first hit the U.S. market in the 1980s, they appeared to be very safe. Since then, however, concerns have been raised about their potential health risks. Evidence has surfaced indicating that the medications may increase the risk for a number of serious side effects including bone fractures, infections and heart attack.
“When they [PPIs] first came out they weren’t associated with side effects, or we didn’t think they were,” said Adam Schoenfeld, an internal medicine resident at the University of California, San Francisco, who authored an editorial that accompanied the study. “So we put [people] on this medication thinking: ‘It’s a quick fix and they’re very safe.’ But in actuality they’re associated with a range of side effects.”
For the study, researchers looked at the medical records of 10,482 participants in the Atherosclerosis Risk in Communities (ARIC) study and 248,751 patients in the Geisinger Health System in Pennsylvania.
Among the 322 PPI users in the ARIC study, the 10-year estimated absolute risk for chronic kidney disease was 11.8%, compared to an expected risk of 8.5%. The 10-year absolute risk among the 16,900 patients using PPIs in the Geisinger Health System was 15.6%, compared with a 13.9% expected risk of chronic kidney disease.
It isn’t clear from these results who is at greatest risk of developing kidney disease from heartburn medications. The study looked only at whether someone had filled a prescription for a PPI, and did not look at how long patients took the drugs.
Do I Have a Proton Pump Inhibitor Lawsuit?
The Product Liability & Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in heartburn drug lawsuits. We are handling individual litigation nationwide and currently accepting new kidney disease cases in all 50 states.
Free Confidential Case Evaluation: Again, if you were injured by heartburn medication side effects, you should contact our law firm immediately. You may be entitled to compensation by filing a class action suit and our lawyers can help.