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Has Cimetidine Been Banned?
What You Need to Know

In January 2020, a number of popular antacids including Zantac (ranitidine) and Axid (nizatidine) were recalled after they were found to be contaminated with the cancer-causing impurity NDMA. Cimetidine, the active ingredient in the heartburn drug Tagamet, did not test positive for NDMA contamination and was not removed from the market.
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If you or a loved one experienced a serious injury from a proton pump inhibitor (PPI), you should contact an attorney immediately.

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What is Cimetidine and How Does it Work?

Cimetidine treats heartburn, stomach ulcers, reflux disease, or other conditions that cause too much stomach acid. The drug works by reducing the amount of acid in the stomach. Cimetidine was approved by the U.S. Food and Drug Administration (FDA) in 1999.

Is it Safe to Take Cimetidine?

Cimetidine is generally considered safe when used as directed. However, you should not take over-the-counter cimetidine for longer than 2 weeks unless your doctor advises you to. If symptoms of heartburn, acid indigestion, or sour stomach last longer than 2 weeks, stop taking cimetidine and consult your physician.

Which Medications Contain Cimetidine?

Cimetidine (Tagamet HB) is available both over-the-counter (OTC) and by prescription. The OTC strength is 200 mg, and the prescription strengths include 200 mg, 300 mg, 400 mg, and 800 mg. OTC dosing: Heartburn symptoms: The typical dose is 200 mg by mouth once a day.

What's the Problem with Cimetidine?

Side effects including headache, dizziness, drowsiness, or diarrhea may occur with the use of cimetidine. If any of these effects persist or worsen, talk to your doctor immediately. If your doctor continues to prescribe cimetidine, they have determined that the benefit to you is greater than the risk of side effects.

Which is Safer, Cimetidine or Omeprazole?

According to a study published in Alimentary Pharmacology & Therapeutics [1], omeprazole, the active ingredient in Nexium, is more effective than cimetidine in the prevention of the recurrence of GERD-associated heartburn and the occurrence of underlying esophagitis. However, Nexium has recently been linked to severe side effects including chronic kidney disease (CKD), interstitial nephritis, heart attack, bone fractures and more.

Related Article: Nexium Lawsuit

How Long Does Cimetidine Stay in Your System?

Cimetidine is rapidly eliminated, with an elimination half-life of approximately 2 hours. It has been said to have a duration of action of 4 to 8 hours. Cimetidine is mainly eliminated in urine.

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