In many cases, gadolinium contrast dyes have been found to remain in the body after the MRI procedure, accumulating in the bones, organs and brain. This is caused by the separation of gadolinium from the rest of the GBCA compound, which prevents it from being expelled from the body. The resulting symptoms are collectively referred to as gadolinium storage condition or gadolinium deposition disease.
Free Confidential Lawsuit Evaluation: If you or a loved one has been diagnosed with gadolinium storage condition or gadolinium deposition disease, you should contact our law firm immediately. You may be entitled to compensation by filing a suit and our lawyers can help.
What is Gadolinium?
Gadolinium is a toxic metal that is commonly used as a contrast agent (“dye”) to enhance the quality of images obtained during an MRI or MRA scan. The dye, which has 7 unpaired electrons — the greatest number of unpaired electron spins possible for an atom, which give off the brightest signal — is injected into a patient’s vein during the procedure. Gadolinium-Based Contrast Agents (“GBCAs”) are used in approximately 20 million MRI/MRA procedures each year in the U.S., according to Advances in Therapy.
Gadolinium Brand Names
- Ablavar (Gadofosveset Trisodium)
- Magnevist (gadopentetate dimeglumine)
- Omniscan (gadodiamide)
- OptiMARK (gadoversetamide)
- MultiHance (gadobenate dimeglumine)
- Prohance (gadoteridol)
FDA Warning on Contrast Agents
The potential temporary and permanent side effects of gadolinium contrast first became well understood about a decade ago, when patients with poor kidney function started being diagnosed with nephrogenic systemic fibrosis (NSF), a skin condition characterized by a swelling and tightening of the skin, usually in the extremities. In 2007, the FDA required gadolinium contrast manufacturers to add a black box warning to their products regarding the risk of NSF.
What is Gadolinium Storage Condition?
The term “gadolinium storage condition” is for patients who have normal renal function, but also left over gadolinium in their brain tissue, bones, or other parts of their body. By contrast, “gadolinium deposition disease” is used to describe patients with adequate renal function who still develop persistent and sometimes painful symptoms a few hours or weeks after receiving gadolinium contrast.
Signs and symptoms of gadolinium storage condition may include:
- Bone pain
- Skin and subcutaneous tissue burning pain
- “Chemo brain” or “brain fog”
- Thickening / discoloration of the skin
These symptoms tend to occur within hours to days of the patient being administered gadolinium contrast dye.
Are There Other Side Effects?
In addition to being linked to gadolinium storage condition / gadolinium deposition disease, the MRI contrast dye has been reported to cause the following side effects in certain patients:
Severe side effects
- Nephrogenic Systemic Fibrosis (NSF)
- Difficulty breathing
- Cardiac arrest
- Swelling of the throat or other parts of the body
- Low blood pressure
Moderate reactions include:
- Severe skin rash or hives
- Abnormal heart rhythms
- High or low blood pressure
- Shortness of breath or difficulty breathing
Mild reactions include:
- Nausea and vomiting
- Mild skin rash or hives
Do I Have a Gadolinium Storage Condition Lawsuit?
The Pharmaceutical Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in gadolinium lawsuits. We are handling individual litigation nationwide and currently accepting new gadolinium storage condition and gadolinium deposition disease cases in all 50 states.
Free Case Evaluation: Again, if you or a loved one has been diagnosed with gadolinium storage condition or gadolinium deposition disease, you should contact our law firm immediately. You may be entitled to compensation by filing a suit and our lawyers can help.