What is Gadolinium?
Gadolinium is an ingredient in contrast agents which are injected in patients undergoing an MRI or other similar medical procedure to enhance the image produced by the machine. Recent studies have found that gadolinium does not leave the body as quickly as the manufacturers stated, and instead remains indefinitely in various parts of the body, putting the patient at risk of exposure to excess gadolinium.
Free Confidential Lawsuit Evaluation: If you or a loved one has been diagnosed with gadolinium deposition disease or gadolinium storage condition, you should contact our law firm immediately. You may be entitled to compensation by filing a suit and our lawyers can help.
FDA Warning on Gadolinium
The U.S. Food and Drug Administration (FDA) has requested the manufacturers of gadolinium-based contrast agents to add a new Boxed Warning on the product labeling because of new reports linking the agents to a life-threatening skin disorder.
The requested boxed warning would state:
“Patients with severe kidney insufficiency who receive gadolinium-based agents are at risk for developing a debilitating, and a potentially fatal disease known as Nephrogenic Systemic Fibrosis (NSF). In addition, it would state that patients just before or just after liver transplantation, or those with chronic liver disease, are also at risk for developing NSF if they are experiencing kidney insufficiency of any severity.”
What are Gadolinium Based Contrast Agents?
Gadolinium-based contrast agents are often used to improve the visibility of internal structures when patients undergo an MRI or MRA. These gadolinium based contrast agents are injected into veins of the patient so that the physician can view a clear and detailed picture of a patient’s internal organs, tissues, bones and/or vessels.
Five gadolinium-based contrast agents have been approved for use in the United States:
- Magnevist (gadopentetate dimeglumine)
- Omniscan (gadodiamide)
- OptiMARK (gadoversetamide)
- MultiHance (gadobenate dimeglumine)
- Prohance (gadoteridol)
What is the MRI or MRA used for?
Magnetic Resonance Imaging (MRIs) and Magnetic Resonance Angiography (MRAs) are typically ordered by physicians in order to detect abnormalities such as tumors, clots, bleeds, and related medical problems.
In August 2016, a study published in the American Journal of Roentgenology described a spectrum of conditions characterized by retention of gadolinium, from asymptomatic patients (Gadolinium Storage Condition) to symptomatic patients (Gadolinium Deposition Disease) to patients with NSF. The researchers found gadolinium deposition disease observed in subjects with normal or near normal renal function who develop persistent symptoms that arise from hours up to 2 months after the administration of GBCA. Signs and symptoms of gadolinium retention include:
- Bone pain
- Skin and subcutaneous tissue burning pain
- “Chemo brain” or “brain fog”
- Skin changes
- Thickening / discoloration of the skin
What is Nephrogenic Systemic Fibrosis (NSF)?
Nephrogenic Systemic Fibrosis (NSF), also known as Nephrogenic Fibrosing Dermopathy (NFD), is a skin condition that is often described as a swelling and tightening of the skin, usually limited to the extremities. The condition may develop over a short period of days or could take weeks to fully develop. Severely affected patients may be unable to walk, or fully extend the joints of their arms, hands, legs, and feet. Complaints of muscle weakness are common.
Do I have a Gadolinium Lawsuit?
The Pharmaceutical Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in gadolinium lawsuits. We are handling individual litigation nationwide and currently accepting new gadolinium deposition disease / gadolinium storage condition cases in all 50 states.
Free Case Evaluation: Again, if you or a loved one has been diagnosed with gadolinium deposition disease or gadolinium storage condition, you should contact our law firm immediately. You may be entitled to compensation by filing a suit and we can help.