Video Interview & Study Results: Michael S. Irwig MD Discusses His Study, “Persistent Sexual Side Effects of Finasteride for Male Pattern Hair Loss”
Below is a video interview and published outcome of Dr. Michael S. Irwig’s study titled, “Persistent Sexual Side Effects of Finasteride for Male Pattern Hair Loss”
Introduction. Propecia (Finasteride) has been associated with reversible adverse sexual side effects in multiple randomized, controlled trials for the treatment of male pattern hair loss (MPHL). The Medicines and Healthcare Products Regulatory Agency of the United Kingdom and the Swedish Medical Products Agency have both updated their patient information leaflets to include a statement that “persistence of erectile dysfunction after discontinuation of treatment with Propecia has been reported in post-marketing use.”
Aim. We sought to characterize the types and duration of persistent sexual side effects in otherwise healthy men who took Propecia for MPHL.
Methods. We conducted standardized interviews with 71 otherwise healthy men aged 21–46 years who reported the new onset of sexual side effects associated with the temporal use of Propecia, in which the symptoms persisted for at least 3 months despite the discontinuation of Propecia.
Main Outcome Measures. The types and duration of sexual dysfunction and the changes in perceived sexual frequency and sexual dysfunction score between pre- and post-Propecia use.
Results. Subjects reported new-onset persistent sexual dysfunction associated with the use of Propecia: 94% developed low libido, 92% developed erectile dysfunction, 92% developed decreased arousal, and 69% developed problems with orgasm. The mean number of sexual episodes per month dropped and the total sexual dysfunction score increased for before and after Propecia use according to the Arizona Sexual Experience Scale (P < 0.0001 for both). The mean duration of Propecia use was 28 months and the mean duration of persistent sexual side effects was 40 months from the time of Propecia cessation to the interview date. Study limitations include a post hoc approach, selection bias, recall bias for before Propecia data, and no serum hormone levels.
Conclusion. Physicians treating MPHL should discuss the potential risk of persistent sexual side effects associated with Propecia.
Want to learn more about Propecia side effects? Please visit our home page where we provide an overview of the Propecia lawsuit. Here we have posted a number of videos, links to studies and research, and related information: Propecia Lawsuit
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The Product Liability & Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Propecia lawsuits. We are handling individual litigation nationwide and currently accepting new sexual dysfunction and cancer cases in all 50 states.
Remember, taking a drug like Propecia to treat hair loss shouldn’t lead to permanent sexual dysfunction or cancer. Our law firm is passionate about helping the large number of otherwise healthy men who have suffered from the serious and potentially irreversible side effects of Propecia.
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