Free Confidential Lawsuit Evaluation: If you or a loved one has been injured by Cipro, you should contact our law firm immediately. You may be entitled to compensation by filing a suit against the manufacturer and our lawyers can help.
Update: Fluoroquinolone Antibiotics May Cause Fatal Heart Damage, FDA Warns
December 21, 2018 – Fluoroquinolones could increase the risk of an aortic dissection, and people who are already at risk should be cautious about taking these medications, the U.S. Food & Drug Administration (FDA) warned in a Drug Safety Communication issued on Thursday.
“A U.S. Food and Drug Administration (FDA) review found that fluoroquinolone antibiotics can increase the occurrence of rare but serious events of ruptures or tears in the main artery of the body, called the aorta,” the agency said. “These tears, called aortic dissections, or ruptures of an aortic aneurysm can lead to dangerous bleeding or even death.”
What is Cipro?
Cipro is an antibiotic medication that belongs to a class of drugs called fluoroquinolones, which are designed to fight bacterial infections of the skin, respiratory / urinary tract, abdomen, and gastrointestinal system. Manufactured by Bayer AG, Cipro was approved by the U.S. Food & Drug Administration (FDA) in 1987, and is available in oral, intravenous, and topical formulations.
Cipro and Peripheral Neuropathy
In August 2013, the FDA issued a Drug Safety Communication which stated that it was requiring Cipro and other fluoroquinolone-containing antibiotics to have their labeling updated to include information about peripheral neuropathy, a potentially irreversible type of nerve damage that can appear rapidly after a patient begins treatment with the drug. According to the FDA:
“The risk of peripheral neuropathy occurs only with fluoroquinolones that are taken by mouth or by injection…The topical formulations of fluoroquinolones, applied to the ears or eyes, are not known to be associated with this risk.”
What is Peripheral Neuropathy?
Peripheral neuropathy occurs when the peripheral nervous system becomes severely damaged. People with the disease may experience tingling, numbness, unusual sensations, weakness, or burning pain in the affected areas. In most patients, symptoms are symmetrical, involving both hands and feet. Because the symptoms typically occur in areas of the body that are covered by gloves or stockings, peripheral neuropathy has been described as having a “glove and stocking” symptom distribution.
Signs and symptoms of peripheral neuropathy may include:
- Change in sensation to light touch, pain, or temperature
- Change in sense of body position
- Loss of reflexes
- Muscle wasting
Treatment of peripheral neuropathy depends on the cause of the disorder. For example, if it is determined to have been caused by Cipro, quitting the drug may lessen symptoms and even reverse nerve damage. However, never stop taking a prescription medication without consulting your physician first.
Early diagnosis is important because the peripheral nerves have a limited capacity to regenerate, and treatment may only slow progression of the disease. If the patient is severely impaired, they may require physical therapy to help regain their strength and avoid muscle cramping and/or spasms.
Fluoroquinolone Antibiotics Linked to Aortic Aneurysm/Dissection
A study published in JAMA Internal Medicine in October 2015 found that fluoroquinolone antibiotics like Cipro may increase users’ risk of developing aortic aneurysm and/or aortic dissection. The researchers noted that fluoroquinolones have previously been found to damage collagen, a structural protein that makes up the aorta. For the study, the researchers looked at data from 1,477 patients who were hospitalized with aortic aneurysm or dissection between January 2000 and December 2011, and compared them to 147,700 controls.
“After propensity score adjustment, current use of fluoroquinolones was found to be associated with increased risk for aortic aneurysm or dissection (rate ratio [RR], 2.43; 95% CI, 1.83-3.22), as was past use, although this risk was attenuated (RR, 1.48; 95% CI, 1.18-1.86),” the researchers said. “Sensitivity analysis focusing on aortic aneurysm and dissection requiring surgery also demonstrated an increased risk associated with current fluoroquinolone use, but the increase was not statistically significant (propensity score–adjusted RR, 2.15; 95% CI, 0.97-4.60)… While these were rare events, physicians should be aware of this possible drug safety risk associated with fluoroquinolone therapy.”
Cipro Side Effects
- Nerve damage
- Peripheral neuropathy
- Aortic Aneurysm
- Muscle weakness
- Tendon ruptures
- Central nervous system disorders
- Hypersensitivity reactions
- Loss of consciousness
- Cardiovascular collapse
- Life-threatening skin reactions
- Toxic epidermal necrolysis (TEN)
- Stevens-Johnson syndrome (SJS)
- Clostridium difficile associated diarrhea
Are Cipro Lawsuits Being Filed?
Yes. In 2003, a group four U.S. postal workers filed a Cipro lawsuit against Bayer. The plaintiffs alleged that they were prescribed Cipro during the 2001 anthrax scare, and shortly thereafter began experiencing severe side effects. The complaint stated that Bayer failed to disclose information regarding the drug’s potential to cause nerve and tendon damage, as well as other serious injuries.
As awareness about the link between Cipro and serious side effects continues to grow, lawyers expect the number of lawsuits filed over the drug will also continue to rise. Patients directly affected by Cipro, as well as relatives of people who have died after taking Cipro, may be eligible to file a claim.
Quinolone Vigilance Foundation
The Quinolone Vigilance Foundation was formed to increase awareness about the dangers of fluoroquinolone antibiotics, and to fund research on the damage caused by the drugs. The group advocates for stronger warnings, and to have fluoroquinolone prescriptions limited to patients with life-threatening infections. Visit the Quinolone Vigilance Foundation for more information about fluoroquinolones and the risks involved with taking them.
Fluoroquinolone MDL Moving Forward in Minnesota
March 22, 2017 – Product liability lawsuits alleging peripheral neuropathy from Levaquin, Cipro and Avelox are moving forward in the U.S. District Court for the District of Minnesota, with at least 10 bellwether cases being prepped for trial. Per a recent update, there are at least 738 lawsuits pending in the fluoroquinolone multidistrict litigation (MDL No. 2642), most of which involve Levaquin.
FDA Updates Boxed Warnings on Fluoroquinolone Antibiotics
July 26, 2016 – For the second time in less than 3 months, the FDA has upgraded warnings on fluoroquinolone antibiotic drugs, saying they’re too strong to be used for sinus infections, bronchitis and simple urinary tract infections (UTIs). “While these drugs are effective in treating serious bacterial infections, an FDA safety review found that both oral and injectable fluoroquinolones are associated with disabling side effects involving tendons, muscles, joints, nerves and the central nervous system,” the agency said in a Drug Safety Communication issued today.
FDA Strengthens Warning on Fluoroquinolone Antibiotics
May 12, 2016 – FDA announced today that unless they lack other treatment options, patients with uncomplicated infections should not be treated with Cipro or other fluoroquinolone antibiotics, given their risk for disabling and potentially life-threatening side effects. Fluoroquinolone warning labels already caution about the risks for tendonitis, tendon rupture, central nervous system (CNS) effects, peripheral neuropathy, myasthenia gravis exacerbation, QT prolongation / torsades de pointes, phototoxicity and hypersensitivity. The agency will update the drugs’ labeling to state that the risks of fluoroquinolones typically outweigh their benefits for patients with sinusitis, bronchitis, and uncomplicated urinary tract infections (UTIs) that are treatable by other means.
Do I have a Cipro Lawsuit?
The Pharmaceutical Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Cipro lawsuits. We are handling individual litigation nationwide and currently investigating potential settlements in all 50 states.
Free Confidential Case Evaluation: Again, if you were injured by Cipro side effects, you should contact our law firm immediately. You may be entitled to a settlement by filing a suit and our lawyers can help.