There have been multiple reports of pancreatitis in Byetta users over the past several years. Warning signs of Byetta pancreatitis may include persistent abdominal pain that can radiate to the back, and may be accompanied by nausea and vomiting. This article will discuss Byetta pancreatitis causes, and how the disease functions.
Byetta Pancreatitis Update 2/26/13: The popular type 2 diabetes drugs Byetta and Januvia may double the risk of users developing pancreatitis, an inflammation of the pancreas that can lead to cancer and kidney failure. The new information, which was published in the journal JAMA Internal Medicine, found that patients hospitalized with pancreatitis were twice as likely to be taking Januvia or Byetta than a control group of diabetics who didn’t have the disease. Click here to learn more.
Free Byetta Lawsuit Evaluation: If you or a loved one has been diagnosed with pancreatic cancer or thyroid cancer after taking Byetta, you should contact our law firm immediately. You may be entitled to compensation by filing a suit against the manufacturer of Byetta and we can help.
How Does Byetta Cause Pancreatitis?
Byetta pancreatitis occurs when digestive enzymes produced in the pancreas become activated while still inside the organ. During normal digestion, the pancreatic enzymes remain inactive until they travel to the small intestine, where they then become active and help with digestion. In patients with Byetta pancreatitis, the enzymes become activated while still in the pancreas, causing severe inflammation and other symptoms associated with the disease. With repeated bouts of Byetta pancreatitis, damage to the organ can lead to chronic pancreatitis, where scar tissue forms and causes loss of function. A poorly functioning pancreas can cause digestion problems and diabetes.
Byetta was approved by the U.S. Food & Drug Administration (FDA) in 2005 for use in controlling type 2 diabetes. The Byetta pen is given by subcutaneous injection, and works to help the pancreas produce insulin more efficiently. However, shortly after being released, reports surfaced alleging that Byetta can cause pancreatitis.
An October 2007 press release issued by the FDA reported at least 30 cases of pancreatitis in Byetta users. Of these, Byetta pancreatitis symptoms typically got worse after the dose was increased from five micrograms twice daily to 10 micrograms two times a day. Twenty-one of the Byetta pancreatitis victims were hospitalized, and five developed serious Byetta side effects which included:
- kidney failure
- intestinal obstruction
- tissue inflammation
- abnormal buildup of fluid in the abdomen
Of the 30 cases of pancreatitis caused by Byetta noted in the 2007 FDA warning, 22 improved after discontinuing use of the drug. In other cases, Byetta pancreatitis symptoms returned after they started taking the drug again. As a result of these reports, the FDA asked Byetta’s manufacturer, Amylin Pharmaceuticals, to include information about Byetta pancreatitis causes on the product label’s ‘precautions’ section.
Less than a year later, the FDA issued an update on Byetta pancreatitis causes. The communication stated that since issuing the original Byetta pancreatitis warning in October 2007, the administration had received at least six additional reports of hemorrhagic or necrotizing pancreatitis in Byetta users. Of the six cases, all patients required emergency hospitalization, two patients died, and four were recovering at the time of reporting. Once again, the FDA advised Amylin to add stronger warnings about Byetta pancreatitis causes to the drug’s label. According to the press release:
“Byetta and other potentially suspect drugs should be promptly discontinued if pancreatitis is suspected. There are no known patient characteristics which determine when pancreatitis associated with Byetta will be complicated by the hemorrhagic or necrotizing forms of this condition. If pancreatitis is confirmed, initiate appropriate treatment and carefully monitor the patient until recovery. Byetta should not be restarted. Consider antidiabetic therapies other than Byetta in patients with a history of pancreatitis.”
Do I Have a Byetta Lawsuit?
The Product Liability & Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Byetta lawsuits. We are handling individual litigation nationwide and currently accepting new Byetta pancreatic cancer and Byetta thyroid cancer cases in all 50 states.
Free Byetta Lawsuit Evaluation: If you or a loved one has been diagnosed with pancreatic cancer or thyroid cancer after taking Byetta, you should contact our law firm immediately. You may be entitled to compensation by filing a Byetta suit and we can help.