The U.S. Food & Drug Administration (FDA) is warning healthcare providers not to prescribe Biaxin to patients with a history of heart problems following the review of a 10-year study of patients with coronary artery disease (CAD).
CLARICOR Trial Results: Increased Death Rate in Biaxin Patients
The CLARICOR Trial: Effect of Clarithromycin on Mortality and Morbidity in Patients With Ischemic Heart Disease, found an unexpected increase in death among patients with coronary heart disease who were prescribed a 2-week course of Biaxin, according to the American Journal of Managed Care (AJMC). Researchers noticed the increased death rate after patients had been followed for 1 year or more, and offered no conclusion on how Biaxin would cause more deaths compared to a placebo.
Heart Attack Symptoms
- Pain / discomfort in the upper body
- Difficulty breathing / shortness of breath
- Sweating or “cold sweat”
- Fullness, indigestion, or choking feeling (may feel like “heartburn”)
- Nausea or vomiting
- Lightheadedness, dizziness, extreme weakness or anxiety
- Rapid or irregular heart beats
What is Biaxin?
Biaxin is prescribed to treat many types of infections affecting the skin, ears, sinuses, lungs, and other parts of the body, including Mycobacterium avium complex (MAC) infection, a type of lung infection that often affects people with HIV/AIDS. Biaxin is manufactured by Takeda Pharmaceuticals, and was first approved by the U.S. Food & Drug Administration (FDA) in December 1995.
Biaxin Side Effects
Serious side effects of Biaxin may include:
- Severe heart damage
- Heart attack
- Sudden death
Other, less severe side effects may include:
- Upset stomach
- Unusual or unpleasant taste in your mouth
- Abdominal pain
- Tooth discoloration
- Itching or rash
- Vaginal itching or discharge