In July 2013, the U.S. Food & Drug Administration (FDA) warned that people who use the blood pressure medication Benicar (olmesartan) may be at risk of developing sprue-like enteropathy. Symptoms of this horrible disease include chronic diarrhea, significant weight loss and villous atrophy. This article discusses the various tests and other methods used to diagnose enteropathy.
Free Benicar Lawsuit Evaluation: If you or a loved one developed enteropathy after using Benicar (olmesartan), you should contact our law firm immediately. You may be entitled to compensation by filing a lawsuit and our lawyers can help.
How is Sprue-Like Enteropathy Diagnosed?
- Serologic Tests – When sprue-like enteropathy is suspected, serologic tests can help to identify affected patients. Studies have shown that lgA antiendomysial antibody is 85 to 100% sensitive, and 96 to 100% specific for celiac disease. IgA antiendomysial antibody is measured by utilizing immunofluorescence of monkey esophagus or umbilical cord tissue processed with the patient’s serum.
- Serologic Tests for Celiac Disease – The presence of IgA antiendomysial and antitransglutaminase antibodies signal that a patient has suffered intestinal damage. Tests for these antibodies are extremely sensitive in individuals with villous atrophy. IgA antiendomysial antibody testing is up to 100% sensitive in patients with total villous atrophy.
It is important to point out that 2 to 3% of patients diagnosed with enteropathy also have selective IgA deficiency. Due to the fact that these individuals may not produce the diagnostic IgA antibodies, a positive IgG antigliadin antibody test may be the only serologic evidence of the condition. If clinical suspicion is high, quantitative IgA measurements may also be obtained from these people. Endoscopy and biopsy should be considered in patients diagnosed with selective IgA deficiency.
- Distal Duodenal Biopsy – Gold standard for the diagnosis of celiac disease. Biopsy should be obtained from patients suspected of having sprue-like enteropathy. In determining the need for biopsy, family practitioners should consult a gastroenterologist who is knowledgable and experienced in the management of celiac disease.
Do I have a Benicar Lawsuit?
The Product Liability & Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Benicar lawsuits. We are handling individual litigation nationwide and currently accepting new Benicar Enteropathy cases in all 50 states.
Free Benicar Lawsuit Evaluation: If you or a loved one was diagnosed with enteropathy after taking Benicar, you should contact our law firm immediately. You may be entitled to compensation by filing a Benicar Suit and our lawyers can help.