The new blood pressure drug Amturnide (generic: aliskiren, amlodipine and hydrochlorothiazide) has recently been linked to serious and potentially life-threatening side effects including strokes, kidney injuries, high potassium levels and low blood pressure. In December 2011, drugmaker Novartis prematurely ended its ALTITUDE clinical trial because a large number of test subjects taking aliskiren-containing medications like Amturnide suffered from these complications. The U.S. Food & Drug Administration (FDA) approved Amturnide to help treat high blood pressure, but the drug is also commonly used in an off-label capacity to treat a variety of other conditions.
Amturnide Update 4/20/12: The FDA issued a warning today to healthcare professionals stating that blood pressure drugs containing aliskiren should not be prescribed to patients with diabetes or kidney impairment with other medications called angiotensin converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs). These drugs are contraindicated, and may result in serious side effects when taken simultaneously.
Free Amturnide Lawsuit Evaluation: If you or a loved one has suffered an injury you feel may have been caused by Amturnide, you should contact our law firm immediately. You may be entitled to compensation by filing a suit against the manufacturer of Amturnide and we can help.
First approved by the FDA in December 2010, Novartis Pharmaceuticals’ Amturnide is a direct renin inhibitor and calcium channel blocker medication designed for the treatment of high blood pressure. The three active ingredients in Amturnide work to lower blood pressure in the following ways:
- Aliskiren – Anti-hypersensitive drug that decreases substances in the body that narrow blood vessels and raise blood pressure.
- Amlodipine – Calcium channel blocker medication that relaxes (widens) blood vessels and improves blood flow.
- Hydrochlorothiazide – Thiazide diuretic (water pill) that helps prevent the body from absorbing too much salt, which can cause fluid retention.
Yet despite its considerable effectiveness at treating high blood pressure, the aliskiren contained in Amturnide has been increasingly associated with a number of serious side effects. In addition to Amturnide, other aliskiren-containing medications include:
- Tekturna (aliskiren)
- Tekturna HCT (hydrochlorothiazide and aliskiren)
- Rasilamlo (aliskiren and amlodipine)
- Rasilez (aliskiren)
- Rasilez HCT (hydrochlorothiazide and aliskiren)
Amturnide Side Effects
The following serious side effects have been reported by Amturnide users:
- kidney problems
- non-fatal strokes
- hyperkalemia (high potassium)
- hypotension (low blood pressure)
- renal complications
Other, less severe side effects associated with Amturnide include:
- slow, uneven heart rate
- weak pulse
- swelling around the eyes
- stomach pain or upset stomach
- itching skin
- skin rash
- back pain
- joint pain
- stuffy nose
- sore throat
Amturnide & Kidney Injury
Amturnide users may suffer kidney injuries when the drug damages blood vessels that supply or drain them. The kidneys may become injured by aneurisms, arterial blockage, arteriovenous fistula, renal vein thrombosis (clotting), and trauma. Signs and symptoms of an Amturnide-induced kidney injury may include:
- abdominal pain
- abdominal swelling
- back pain
- blood in the urine
- decreased alertness
- decreased urine output
- flank pain
- increased heart rate
- inability to urinate
- pale skin
- skin cool to touch
Long-term (chronic) symptoms may include:
- weight loss
Amturnide & Strokes
Seeing as Amturnide has the ability to manipulate blood flow, it may also increase the risk of stroke in certain patients. If blood flow is stopped for longer than a few seconds, the brain cannot get oxygen and blood. If the condition is not treated in a timely manner, brain cells die, causing permanent damage. Signs and symptoms of an Amturnide-induced stroke may include:
- numbness on one side of the body
- loss of vision / problems with vision
- change in alertness
- sudden intense headache
On December 20, 2011, Novartis issued a press release stating that it had prematurely ended its ALTITUDE clinical trial because an abnormally high number of test subjects who had taken aliskiren for more than 18 months had reported non-fatal strokes, heart problems and kidney injuries. ALTITUDE involved more than 8,600 patients from 36 countries. Despite the fact that Novartis has yet to issue a nationwide recall for Amturnide and its other aliskiren-containing medications, the company has voluntarily halted promotion of the drugs until the results of the study can be fully evaluated by health authorities.
Do You Have an Amturnide Lawsuit?
The Product Liability & Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Amturnide lawsuits. We are handling individual litigation nationwide and currently accepting new stroke, kidney injury and low blood pressure cases in all 50 states.
Free Amturnide Lawsuit Evaluation: If you or a loved one has suffered an injury you feel may have been caused by Amturnide, you should contact our law firm immediately. You may be entitled to compensation by filing an Amturnide injury suit and we can help.