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Nexium Bone Fracture Lawsuit

Nexium Bone Fracture Lawsuit

AstraZeneca’s widely-prescribed heartburn drug Nexium (esomeprazole magnesium) has recently been linked to bone fractures and bone breaks, particularly among users who have taken the drug over an extended period of time. In May 2010, the U.S. Food & Drug Administration (FDA) required that labels of Nexium and other proton pump inhibitor (PPI) drugs be updated to include information about this risk. Nexium fractures have been reported to involve a number of different bones including the ribs, ankles, feet, hip, wrist and spine.

Free Nexium Bone Fracture Lawsuit Evaluation: If you or a loved one has suffered a bone fracture after taking Nexium, you should contact our law firm immediately. You may be entitled to compensation by filing a suit against the manufacturer of Nexium and we can help.

Nexium Overview

First approved by the FDA in February 2001, Nexium is a proton pump inhibitor drug used to treat the symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid. It is AstraZeneca’s best-selling drug, as well as the third best-selling medication in the world, generating over $5.2 billion in sales in 2008 alone. Esomeprazole, the active ingredient in Nexium, is now manufactured by several companies under the brand names:

Nexium Bone Fractures

It has been theorized that Nexium has the potential to cause bone fractures because it reduces acid in the stomach, which in turn lowers the amount of calcium dissolved and absorbed into the body. Nexium also interferes with the body’s ability to break down and rebuild bone by manipulating the acid production of osteoclasts. Additionally, the reduction of B-12 by raising homocysteine may make the bones more fragile and prone to fractures or breaks.

“Epidemiology studies suggest a possible increased risk of bone fractures with the use of proton pump inhibitors for one year or longer, or at high doses,” said Dr. Joyce Korvick, FDA’s Division of Gastroenterology Products deputy director for safety. “Because these products are used by a great number of people, it’s important for the public to be aware of this possible increased risk and, when prescribing proton pump inhibitors, health care professionals should consider whether a lower dose or shorter duration of therapy would adequately treat the patient’s condition.”

FDA Warning on Nexium

The FDA’s review of several long-term studies which found an increased risk of hip, wrist, and spine fractures in PPIs users prompted the administration in May 2010 to revise labeling requirements for the drugs. The research indicated that these fractures occurred more often in patients who used PPIs like Nexium for more than one year at a higher dose. Then in 2011, researchers reiterated the fact that the risk of bone fractures greatly increased when using PPIs. Scientists found that PPI users who smoked had a 51% increased risk of suffering a hip fracture, and concluded that the longer the duration of use, the greater the risk of a fracture.

Nexium Bone Fracture Lawsuit Filed in Texas

In April 2011, a lawsuit was filed on behalf of an Ohio woman who suffered severe bone deterioration and broken bones after taking Nexium. Filed in the U.S. District Court in Houston, the complaint alleges that 58-year-old Ginny Begin suffered serious bone deterioration after taking Nexium on a daily basis from 2003 until early 2011. According to the lawsuit, “[A]s early as 2006, studies found PPI’s, by reducing hydrochloric acid in the stomach, interfere with the body’s ability to absorb calcium, thus speeding up bone loss and leading to an increased number of fractures. In total, six studies have found the risk of fracture significantly increased for those patients over 50 years of age who took a prescription-strength PPI, like Nexium, or who took any PPI regularly for more than one year. Specifically, use of PPI’s increases the risk of fractures in women up to 34 percent.”

Do I Have a Nexium Bone Fracture Lawsuit?

The Product Liability & Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Nexium lawsuits. We are handling individual litigation nationwide and currently accepting new bone fracture cases in all 50 states.

Free Nexium Bone Fracture Lawsuit Evaluation: If you or a loved one has suffered a serious bone fracture after taking Nexium, you should contact our law firm immediately. You may be entitled to compensation by filing a Nexium bone fracture suit and we can help.

U.K. Issues Proton Pump Inhibitor (PPI) Bone Fracture Warnings

Proton Pump Inhibitor Bone Fracture Lawsuit

U.K. health regulators have issued two new warnings to the public stating that the use of proton pump inhibitor (PPI) heartburn drugs may cause bone fractures, and have the potential to lead to dangerously low levels of magnesium in the body. According to the warnings, these risks are increased if high doses of PPIs are taken over long periods of time, and appear to primarily affect the elderly. Heartburn drugs belonging to the PPI class include Nexium, Prilosec, Protonix, Prevacid, Aciphex, Dexilant, Vimovo and Zegerid.

Free Proton Pump Inhibitor Lawsuit Evaluation: If you or a loved one has suffered a serious bone fracture you believe may have been caused by a proton pump inhibitor drug, you should contact our law firm immediately. You may be entitled to compensation by filing a suit against the manufacturer of the proton pump inhibitor and we can help.

What’s the problem?

April 25, 2012 – During the month of April, the United Kingdom’s Medicines and Healthcare Products Regulatory Agency (MHRA) issued two separate warnings regarding the following proton pump inhibitor heartburn medications:

The first warning stated that new evidence indicates an increased risk of hip, spine and wrist fractures associated with PPI use. The MHRA advised patients taking the medications to be sure they are getting enough calcium and vitamin D in their diets to reduce the bone fracture risk.

The other warning involved severe cases of magnesium deficiency (also known as hypomagnesaemia) which have been increasingly linked to PPIs. According to the statement, magnesium deficiency is associated with long-term use of the drugs at high doses. This evidence came from a review of adverse event reports sent to health authorities across Europe. In severe cases, hypomagnesaemia can cause fatigue, delirium, convulsion, dizziness, and other serious side effects.

Proton pump inhibitors are designed to reduce the amount of acid in the stomach, and are generally prescribed to treat the following conditions:

  • gastroesophageal reflux disease (GERD)
  • heartburn
  • ulcers in the stomach and small intestines
  • inflammation of the esophagus

In May 2010, the U.S. Food & Drug Administration (FDA) issued a warning stating that there may be an increased risk of bone fractures from PPI heartburn medications. The warning was updated a year later with an indication that this risk was linked to high doses of the drugs taken over prolonged periods of time. According to the FDA, this risk does not apply to over-the-counter PPIs.

The consumer watchdog group Public Citizen has petitioned the FDA to require black box warnings to be added to PPI labels, alerting users that the drugs have been linked to bone fractures and can cause dependency in a relatively short period of time.

Over the past several years, a growing number of PPI bone fracture lawsuits have been filed in courthouses around the country. The claims allege that drugmakers failed to adequately research their drugs and neglected to warn the public about the risk of bone fractures.

Do You Have a Proton Pump Inhibitor Bone Fracture Lawsuit?

The Product Liability & Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in proton pump inhibitor lawsuits. We are handling individual litigation nationwide and currently accepting new bone fracture cases in all 50 states.

Free Proton Pump Inhibitor Lawsuit Evaluation: If you or a loved one has suffered a serious bone fracture you believe may have been caused by a proton pump inhibitor drug, you should contact our law firm immediately. You may be entitled to compensation by filing a proton pump inhibitor bone fracture suit and we can help.

Nexium & Prilosec Bone Fracture Lawsuit Filed Against AstraZeneca

Nexium Prilosec Bone Fracture Lawsuit

A lawsuit has been filed against AstraZeneca on behalf of a woman who allegedly suffered catastrophic foot fractures after taking Nexium and Prilosec. According to the claim, the side effects of the popular heartburn drugs made her bones brittle after long-term use, resulting in multiple breaks and a lifetime of expensive medical treatment. This latest case is just one of a multitude of similar lawsuits filed around the country in recent months, all of which claim that AstraZeneca failed to adequately warn the public about the risk of Nexium and Prilosec bone fractures.

Free Nexium / Prilosec Bone Fracture Case Evaluation: If you or a loved one has suffered a bone fracture or other serious side effect after taking Nexium or Prilosec, you should contact our law firm immediately. You may be entitled to compensation by filing a lawsuit and we can help.

What’s the problem?

July 14, 2011 – The new product liability claim, which was filed against AstraZeneca on behalf of Susan A. Poznavich in New Jersey Superior Court in Bergen County, alleges that the woman suffered a number of severe foot fractures after taking Nexium and Prilosec, popular heartburn drugs that have garnered extensive media coverage recently after being linked to an increased risk of bone problems.

Poznavich’s claim is just one of a growing number of lawsuits filed by Nexium and Prilosec users in recent months. In May 2011, a claim was filed on behalf of 35 people in Texas who allegedly suffered bone deterioration and fractures after taking Nexium. The lawsuit was filed in Harris County District Court against AstraZeneca and a Houston-area sales manager, claiming that despite having knowledge of the side effects associated with the drug, Nexium was marketed and sold to the public without adequate warnings for consumers. According to the suit, Nexium caused various injuries to the plaintiffs including fractures of the foot, ankle, leg, arm, hand, knee and vertebrae.

Proton Pump Inhibitors (PPIs)

Nexium (esomeprazole) and Prilosec (omeprazole) belong to a class of drugs known as proton pump inhibitors (PPIs), whose main action is a pronounced and long-lasting reduction of gastric acid production. PPIs are extremely popular and widely used, with doctors writing nearly 115 million prescriptions for the medications each year nationwide. Nexium is AstraZeneca’s best selling prescription drug, as well as the third best-selling medication in the world, with over $5.2 billion in sales in 2008 alone. In addition to Nexium and Prilosec, other drugs in the PPI class include:

In May 2010, the U.S. Food & Drug Administration (FDA) warned that there may be an increased risk of bone fractures from these drugs. In March 2011, the administration updated its Nexium bone fracture warning, highlighting the fact that the risk of broken bones appears to be linked to high doses of the drugs used over an extended period of time.

Side Effects of Nexium & Prilosec

Studies have shown that the use of PPI medications like Nexium and Prilosec may greatly increase the risk of a number of side effects including:

  • hip fractures
  • wrist fractures
  • spine fractures
  • abdominal pain
  • constipation
  • nausea
  • diarrhea
  • stroke
  • allergic reactions
  • heart attack
  • weight loss
  • erectile dysfunction (ED)

Nexium & Prilosec FDA Warning

In May 2010, the FDA issued a press release stating that it was requiring the labels of PPI drugs like Nexium and Prilosec to be revised. The press release informed the public that PPIs may increase the risk of wrist, hip and spine fractures. In the announcement, the FDA advised users and doctors to weigh the benefits vs. risks of these medications closely before beginning a regimen. The following statement illustrates the dangers associated with PPIs:

“Epidemiology studies suggest a possible increased risk of bone fractures with the use of proton pump inhibitors for one year or longer, or at high doses,” said Dr. Joyce Korvick, FDA’s Division of Gastroenterology Products deputy director for safety. “Because these products are used by a great number of people, it’s important for the public to be aware of this possible increased risk and, when prescribing proton pump inhibitors, health care professionals should consider whether a lower dose or shorter duration of therapy would adequately treat the patient’s condition.”

Do I have a Nexium / Prilosec Bone Fracture Lawsuit?

The Product Liability & Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Nexium and Prilosec lawsuits. We are handling individual litigation nationwide and currently accepting new bone fracture cases in all 50 states.

Dexilant Lawsuit

Dexilant Lawsuit

The link between bone fractures and ingestion of the popular heartburn medication Dexilant has been the basis for an increasing number of lawsuits being filed around the country. Dexilant is an FDA-approved drug normally prescribed to treat gastroesophageal disease (GERD) and other conditions involving excess stomach acid. Nationwide, lawsuits are emerging claiming that Dexilant’s manufacturer Takeda did not provide adequate warnings about the possibility of bone fractures.

Dexilant Update 4/25/12: U.K. health regulators have issued two new warnings to the public stating that the use of proton pump inhibitor (PPI) heartburn drugs may cause bone fractures, and have the potential to lead to dangerously low levels of magnesium in the body. According to the warnings, these risks are increased if high doses of PPIs are taken over long periods of time, and appear to primarily affect the elderly. Click here to learn more.

Proton Pump Inhibitor (PPI) Update 2/8/12: The U.S. Food & Drug Administration (FDA) issued a warning today stating that the use of proton pump inhibitor heartburn drugs may increase the risk of Clostridium difficile-associated diarrhea. FDA’s warning came in response to a safety review from its Adverse Event Reporting System that suggested such a link. Click here to learn more.

Free Dexilant Case Evaluation: If you or a loved one has been injured by Dexilant, you should contact our law firm immediately. You may be entitled to compensation by filing a lawsuit and we can help.

What’s the problem?

Dexilant is a proton pump inhibitor (PPI) drug whose main function is to reduce the production of gastric acid in the stomach. These medications are among the most widely prescribed drugs in the world, and are generally considered very effective. PPI medications have largely replaced the use of H2-receptor antagonists, which work by blocking the action of histamine on parietal cells in the stomach. Dexilant has been approved by the U.S. Food & Drug Administration (FDA) for the treatment of the following conditions:

  • Dyspepsia;
  • Peptic Ulcer Disease;
  • Gastroesophageal disease (GERD);
  • Laryngopharyngeal Reflux;
  • Barrett’s Esophagus;
  • the prevention of stress gastritis;
  • Gastrinomas;
  • Zollinger-Ellison syndrome.

Despite their widespread use, the effectiveness of proton pump inhibitors has not been demonstrated in all of the above conditions. For example, PPIs do not change the length of Barrett’s esophagus. Other PPI medications in the same class as Dexilant include:

Side Effects of Dexilant

Unfortunately, studies have shown that the use of proton pump inhibitor drugs like Dexilant may greatly increase the risk of a number of side effects including:

  • Hip fractures
  • Wrist fractures
  • Spine fractures
  • Abdominal pain
  • Constipation
  • Nausea
  • Diarrhea
  • Stroke
  • Allergic reactions
  • Heart attack
  • Weight loss
  • Erectile Dysfunction (ED)

Dexilant Bone Fractures

According to new data from an ongoing Nurses’ Health Study, the side effects of Dexilant and other PPI drugs increase the risk of bone fractures, particularly among women who smoke. The study began focusing on bone fractures in 1982, and includes some 238,000 participants. Researchers found that women who smoke or used to smoke and regularly took a PPI had a 51% increased risk of suffering a hip fracture. Women who did not smoke only had a 6% increased risk when taking a PPI. The new study is just the latest in a series of independent and government research that has linked an increased risk of bone fractures to PPI medications like Dexilant.

The severity of the bone fracture depends on a variety of factors including the propensity to fall, visual acuity, response to falling and bone strength. Bone mass is the single most important factor in determining bone strength, and accounts for up to 80% of its variance. Fracture sites, on the other hand, are typically age related. Wrist fractures are common for people in their fifties, while those in their sixties are most susceptible to spine fractures. By the time an individual reaches their seventies, the hip becomes the most common site of osteoporotic fracture.

Dexilant FDA Warning

In May 2010, the FDA issued a safety announcement stating that it was revising the labels of PPI drugs. The warning alerted patients that this class of drugs may increase the risk of wrist, hip and spine fractures. In the press release, the administration advised users and their doctors to weigh the known benefits of these medications against the significant risks. The following statement illustrates the dangers associated with Dexilant and other PPI’s:

“Epidemiology studies suggest a possible increased risk of bone fractures with the use of proton pump inhibitors for one year or longer, or at high doses,” said Dr. Joyce Korvick, FDA’s Division of Gastroenterology Products deputy director for safety. “Because these products are used by a great number of people, it’s important for the public to be aware of this possible increased risk and, when prescribing proton pump inhibitors, health care professionals should consider whether a lower dose or shorter duration of therapy would adequately treat the patient’s condition.”

If You Are Taking Dexilant

Since heartburn is often confused with the first symptoms of a heart attack, seek immediate medical attention if you have chest pain or pain spreading to the arm or shoulder. You should not take Dexilant if you have a family history of liver disease or low levels of magnesium in your blood. Tell your doctor if you have osteoporosis or osteopenia (low bone mineral density). Dexilant is currently classified as a Pregnancy Category B medication, meaning that it is not expected to cause birth defects. Do not use Dexilant if you are breast feeding a baby, as the drug may pass into breast milk and could harm a nursing child.

Do I have a Dexilant Lawsuit?

The Product Liability & Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Dexilant lawsuits. We are handling individual litigation nationwide and currently accepting new bone fracture cases in all 50 states.

Nexium Bone Fracture Lawsuit Filed by 35 in Texas

Nexium Bone Fracture Lawsuit

June 1, 2011 – A new lawsuit has been filed against AstraZeneca on behalf of 35 Texas residents who claim to have suffered from unexpected bone fractures and deterioration after using Nexium, the company’s best-selling heartburn medication. According to the claim, Nexium caused various injuries including fractures of the foot, ankle, leg, arm, hand, knee and vertebrae. Since 2006, studies have suggested that Nexium may block the body’s ability to absorb calcium, which speeds up bone loss and leads to an increased number of fractures.

Free Nexium Case Evaluation: If you or a loved one has been injured by Nexium, you should contact our law firm immediately. You may be entitled to compensation by filing a lawsuit and we can help.

What’s the problem?

The new Nexium lawsuit was filed last week in Harris County District Court against pharmaceutical giant AstraZeneca and a Houston-area sales manager, claiming that despite having knowledge of the side effects associated with the drug, Nexium was marketed and sold to the public without adequate warnings for consumers. The complaint was filed on behalf of 34 women and one nine-year-old boy who experienced adverse side effects after taking the heartburn medication.

Included in the complaint are reports of foot, ankle, leg, arm, hand, knee and vertebrae fractures. A number of the plaintiffs suffered these injuries with no external trauma, resulting in surgery or permanent disability in many cases. Additionally, bone density scans revealed extensive bone deterioration and osteoporosis in many of the plaintiffs, despite having no family history of the conditions.

First approved by the U.S. Food & Drug Administration (FDA) in 2001, Nexium is a proton pump inhibitor (PPI) drug designed to decrease the amount of acid in the stomach. The drug is most often prescribed to treat gastroesophageal reflux disease (GERD), but is also commonly used to treat other conditions involving excessive stomach acid. Nexium is AstraZeneca’s best selling drug, as well as the third best selling medication in the world with over $5 billion in sales in 2008 alone.

FDA Warning on Nexium

In May 2010, the FDA issued a press release warning of the increased risk of bone fractures from Nexium and other PPI drugs including Aciphex, Prevacid, Prilosec, Protonix, Vimovo and Zegerid. In the announcement, the administration said that it was requiring an update to the warning labels of these medications reflecting the new information about bone fracture risks. Then in March 2011, the FDA again updated its Nexium bone fracture warning, stating that the side effects were associated with high doses of the drugs over a long period of time.

Do I have a Nexium Lawsuit?

The Product Liability & Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Nexium lawsuits. We are handling individual litigation nationwide and currently accepting new bone fracture cases in all 50 states.

Proton Pump Inhibitor (PPI) Lawsuit

Proton Pump Inhibitor Lawsuit

Proton pump inhibitor (PPI) medications are commonly prescribed to individuals with heartburn and acid reflux disease. These drugs work by blocking acid buildup in the stomach. However, they also block calcium absorption, which may lead to a number of adverse side effects including wrist, spine and hip fractures.

Proton Pump Inhibitor Update 4/25/12: U.K. health regulators have issued two new warnings to the public stating that the use of proton pump inhibitor (PPI) heartburn drugs may cause bone fractures, and have the potential to lead to dangerously low levels of magnesium in the body. According to the warnings, these risks are increased if high doses of PPIs are taken over long periods of time, and appear to primarily affect the elderly. Click here to learn more.

Free Proton Pump Inhibitor Case Evaluation: If you or a loved one has suffered an injury due to any of the PPI medications listed in this article, you should contact our law firm immediately. You may be entitled to compensation by filing a lawsuit and we can help.

What are Proton Pump Inhibitor (PPI) Drugs?

PPIs are widely prescribed for the treatment of various acid-peptic disorders including gastroesophageal reflux disease (GERD), peptic ulcer disease, and nonsteroidal anti-inflammatory drug­induced gastropathy. These drugs work by reducing the production of acid by blocking the enzyme in the wall of the stomach that produces acid. This reduction of acid prevents ulcers and allows any existing ulcers to heal.

Unfortunately, mounting evidence and numerous case studies have found that long-term use of PPI medications may cause problems with the body’s ability to absorb calcium. Patients using PPIs for an extended period of time (typically over one year) are at risk of suffering fractures of the hips, wrists, forearms and spines. Particularly at risk are women over 50 and those who are post-menopausal.

Proton Pump Inhibitor (PPI) Side Effects

Proton pump side effects have been reported to include the following:

  • Hip fractures
  • Wrist fractures
  • Spine fractures
  • Abdominal pain
  • Constipation
  • Nausea
  • Diarrhea
  • Stroke
  • Allergic reactions
  • Heart attack
  • Weight loss
  • Erectile Dysfunction (ED)

On May 25, 2010, the U.S. Food & Drug Administration (FDA) published information regarding the increased risk of fractures of the hip, wrist, and spine with high doses or long-term use of PPIs. The product labeling on such medications was ordered to be changed to describe this possible increased risk. The Administration’s decision to revise the labeling of PPIs was reportedly based on the review of several epidemiological studies that reported an increased risk of fractures of the hip, wrist and spine in patients using proton pump inhibitors.

“Epidemiology studies suggest a possible increased risk of bone fractures with the use of proton pump inhibitors for one year or longer, or at high doses,” said Joyce Korvick, M.D., deputy director for safety in FDA’s Division of Gastroenterology Products. “Because these products are used by a great number of people, it’s important for the public to be aware of this possible increased risk and, when prescribing proton pump inhibitors, health care professionals should consider whether a lower dose or shorter duration of therapy would adequately treat the patient’s condition.”

Types of Proton Pump Inhibitors

The following proton pump inhibitor brands have been included in the FDA’s new warning:

 

Do You Have a Proton Pump Inhibitor (PPI) Lawsuit?

The Product Liability & Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in proton pump inhibitor (PPI) lawsuits. We are handling individual litigation nationwide and currently accepting new bone fracture cases in all 50 states.

Zegerid Lawsuit

Zegerid Lawsuit

According to the FDA, the heartburn medication Zegerid raises the risk of bone fractures, especially when used for a year or more at high doses. Unfortunately, many patients taking Zegerid may be unaware of the potentially dangerous side effects associated with this medication. An ever increasing number of bone fracture cases have been reportedly linked to Zegerid.

Zegerid Update 4/25/12: U.K. health regulators have issued two new warnings to the public stating that the use of proton pump inhibitor (PPI) heartburn drugs may cause bone fractures, and have the potential to lead to dangerously low levels of magnesium in the body. According to the warnings, these risks are increased if high doses of PPIs are taken over long periods of time, and appear to primarily affect the elderly. Click here to learn more.

Proton Pump Inhibitor (PPI) Update 2/8/12: The U.S. Food & Drug Administration (FDA) issued a warning today stating that the use of proton pump inhibitor heartburn drugs may increase the risk of Clostridium difficile-associated diarrhea. FDA’s warning came in response to a safety review from its Adverse Event Reporting System that suggested such a link. Click here to learn more.

Free Zegerid Case Evaluation: If you or a loved one has suffered from a bone fracture or other adverse event you feel may have been caused by Zegerid, you should contact our law firm immediately. You may be entitled to compensation by filing a lawsuit and we can help.

What’s the problem?

Zegerid (omeprazole / sodium bicarbonate) is a heartburn medication typically prescribed to treat acid reflux disease. It is also less commonly prescribed to treat erosive esophagitis, active duodenal ulcers and active benign gastric ulcers. A nonprescription version – Zegerid OTC – is also available for the short treatment of frequent heartburn. Prescription Zegerid capsules are made by Norwich Pharmaceuticals, Inc., for Santarus, Inc.

Side Effects of Zegerid

A number of Zegerid side effects have been reported in users including:

  • Hip fractures
  • Wrist fractures
  • Spine fractures
  • Abdominal pain
  • Constipation
  • Nausea
  • Diarrhea
  • Stroke
  • Allergic reactions
  • Heart attack
  • Weight loss
  • Erectile Dysfunction (ED)

Zegerid should not be taken by people with a hypersensitivity to omeprazole or sodium bicarbonate. Women who are pregnant or planning to become pregnant should discuss Zegerid with their healthcare professional prior to taking the medication. To date, there have been no clinical studies on the effects of Zegerid in pregnant women and nursing mothers.

Zegerid Bone Fractures

In May 2010, the U.S. Food & Drug Administration (FDA) required that additional information be provided about the risk of Zegerid bone fractures on its packaging as well as the packaging of other similar heartburn medications. The Administration stated that all proton pump inhibitor medications will now include a warning that they may increase the risk of fracturing bones in the hips, wrist, and spine.

“Epidemiology studies suggest a possible increased risk of bone fractures with the use of proton pump inhibitors for one year or longer, or at high doses,” said Dr. Joyce Korvick, FDA’s Division of Gastroenterology Products deputy director for safety. “Because these products are used by a great number of people, it’s important for the public to be aware of this possible increased risk and, when prescribing proton pump inhibitors, health care professionals should consider whether a lower dose or shorter duration of therapy would adequately treat the patient’s condition.”

Proton pump inhibitors required to carry the enhanced warnings include:

FDA’s decision to revise the labeling of proton pump inhibitors was based on the Agency’s review of several epidemiological studies that reported an increased risk of fractures of the hip, wrist and spine in patients using PPIs. Both the Warnings and Precautions section of the prescription labeling and the Drug Facts label on OTC proton pump inhibitors will address these findings.

Do I have a Zegerid Lawsuit?

The Product Liability & Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Zegerid lawsuits. We are handling individual litigation nationwide and currently accepting new bone fracture cases in all 50 states.

Vimovo Lawsuit

Vimovo Lawsuit

On March 2, 2011, the U.S. Food & Drug Administration (FDA) issued a warning about the risk of severe bone fractures with PPI medications like Vimovo (naproxen & esomeprazole magnesium). Vimovo is intended for use in the treatment of osteoarthritis and gastric ulcers, but it now seems that the risk of taking the drug may be greater than any potential benefit. Lawsuits are now being investigated nationwide of behalf of individuals who have suffered from Vimovo side effects.

Proton Pump Inhibitor (PPI) Update 2/8/12: The U.S. Food & Drug Administration (FDA) issued a warning today stating that the use of proton pump inhibitor heartburn drugs may increase the risk of Clostridium difficile-associated diarrhea. FDA’s warning came in response to a safety review from its Adverse Event Reporting System that suggested such a link. Click here to learn more.

Free Vimovo Case Evaluation: If you or a loved one has suffered from a bone fracture or other adverse side effect after taking Vimovo, you should contact our law firm immediately. You may be entitled to compensation by filing a lawsuit and we can help.

What’s the problem?

Marketed and manufactured by AstraZeneca, Vimovo was first approved by the U.S. Food & Drug Administration (FDA) in May 2010 for the treatment of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Vimovo is a combination of the pain killer naproxen and esomeprazole magnesium, which is the active ingredient in the heartburn drug Nexium. It is a proton pump inhibitor (PPI) medication intended for use by those who have gastric ulcers, a common side effect of other drugs that treat those conditions.

Proton pump inhibitor drugs like Vimovo work by reducing the amount of acid in the stomach. In 2009 alone, approximately 21 million PPI prescriptions were filled at retail pharmacies around the country. Medications in the PPI class include:

Unfortunately, studies have shown that the use of such medications may greatly increase the risk of a number of side effects including severe bone fractures of the wrist, hip and spine. Research indicates that Vimovo may weaken the dexterity of bones and allow minimal pressure to cause a fracture.

Vimovo Side Effects

Vimovo side effects typically appear in individuals 50 and older who take the medication for a year or longer. Serious side effects most often reported in Vimovo users include:

  • Hip fractures
  • Wrist fractures
  • Spine fractures
  • Abdominal pain
  • Constipation
  • Nausea
  • Diarrhea
  • Stroke
  • Allergic reactions
  • Heart attack
  • Weight loss
  • Erectile Dysfunction (ED)

Vimovo & Hypomagnesemia

On March 2, 2011, the FDA announced that it was notifying the public and medical communities that PPI drugs like Vimovo may also cause low serum magnesium levels (hypomagnesemia) if taken for prolonged periods of more than one year. Low serum magnesium levels can result in a number of adverse side effects including muscle spasm (tetany), irregular heartbeat (arrhythmias), and convulsions. FDA recommends that doctors should consider obtaining serum magnesium levels prior to initiation of prescription PPI treatment in patients expected to be on these medications for longer than a year, as well as individuals who take PPIs in combination with drugs such as digoxin, diuretics or medications that may cause hypomagnesemia.

Do I have a Vimovo Lawsuit?

The Product Liability & Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Vimovo lawsuits. We are handling individual litigation nationwide and currently accepting new bone fracture cases in all 50 states.

Protonix Lawsuit

Protonix Lawsuit

Attention Protonix Users: There is evidence that this heartburn medication and others in its class increase the risk of fractures of the spine, hip and wrist. If you’ve suffered from serious bone fractures or other side effects while taking Protonix, you may be eligible to file a Protonix lawsuit and recover compensation for your injuries.

Protonix Update 4/25/12: U.K. health regulators have issued two new warnings to the public stating that the use of proton pump inhibitor (PPI) heartburn drugs may cause bone fractures, and have the potential to lead to dangerously low levels of magnesium in the body. According to the warnings, these risks are increased if high doses of PPIs are taken over long periods of time, and appear to primarily affect the elderly. Click here to learn more.

Proton Pump Inhibitor (PPI) Update 2/8/12: The U.S. Food & Drug Administration (FDA) issued a warning today stating that the use of proton pump inhibitor heartburn drugs may increase the risk of Clostridium difficile-associated diarrhea. FDA’s warning came in response to a safety review from its Adverse Event Reporting System that suggested such a link. Click here to learn more.

Free Protonix Case Evaluation: If you or a loved one has suffered from injuries you feel may have been caused by Protonix, you should contact our law firm immediately. You may be entitled to compensation by filing a lawsuit and we can help.

What’s the problem?

Protonix (generic: pantoprazole) is a proton pump inhibitor (PPI) medication used in the treatment of peptic ulcer disease. It is chemically structured to help the secretion of acid from the stomach glands. There are generic brands of Protonix, but the drug usually comes in a 40mg oral medicine tablet that is delayed-release and long lasting. Protonix was developed by Atlanta and is currently marketed by Wyeth-Ayerst Laboratories.

To relieve the symptoms of gastric reflux, many patients are prescribed Protonix for a period of several months or longer. For many, the relief Protonix brings is welcomed. However, mounting evidence and numerous case studies have shown that Protonix and other PPIs may cause harm to some patients.

Side Effects of Protonix

Protonix side effects typically appear in individuals 50 and older who take the medication for a year or longer. Serious side effects most often reported in Protonix users include the following:

  • Hip fractures
  • Wrist fractures
  • Spine fractures
  • Abdominal pain
  • Constipation
  • Nausea
  • Diarrhea
  • Stroke
  • Allergic reactions
  • Heart attack
  • Weight loss
  • Erectile Dysfunction (ED)

PPI medications like Protonix have been linked to a possible increase in the risk of fractures because the drugs reduce the acid in the stomach that block against harmful bacteria. Fractured hips, wrists and spines are serious and painful injuries which can severely restrict mobility and limit the patient’s quality of life. Long-term use of PPIs like Protonix in older patients may increase the risk of suffering hip fractures by up to 25%. Proton pump inhibitor medications include:

Precautions when taking Protonix

Since Protonix contains sodium, patients who are on salt restricted diets like those with heart failure should avoid taking the medication. Because it may cause bleeding, patients taking blood thinning agents should be careful while taking protonix. The safety of this medication in pregnant women has not been proven and is not recommended for women who are pregnant or planning to become pregnant.

Do I have a Protonix Lawsuit?

The Product Liability & Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Protonix lawsuits. We are handling individual litigation nationwide and currently accepting new bone fracture cases in all 50 states.

Prilosec Lawsuit

Prilosec Lawsuit

The proton pump inhibitor (PPI) drug Prilosec is generally prescribed to treat the symptoms of heartburn. Prilosec and other PPI medications are chemically designed to block acid buildup. However, Prilosec may also block calcium absorption, which may lead to wrist, spine and hip fractures in some patients.

Prilosec Update 4/25/12: U.K. health regulators have issued two new warnings to the public stating that the use of proton pump inhibitor (PPI) heartburn drugs may cause bone fractures, and have the potential to lead to dangerously low levels of magnesium in the body. According to the warnings, these risks are increased if high doses of PPIs are taken over long periods of time, and appear to primarily affect the elderly. Click here to learn more.

Proton Pump Inhibitor (PPI) Update 2/8/12: The U.S. Food & Drug Administration (FDA) issued a warning today stating that the use of proton pump inhibitor heartburn drugs may increase the risk of Clostridium difficile-associated diarrhea. FDA’s warning came in response to a safety review from its Adverse Event Reporting System that suggested such a link. Click here to learn more.

Free Prilosec Case Evaluation: If you or a loved one has suffered from a bone fracture or other adverse event you feel may have been caused by Prilosec, you should contact our law firm immediately. You may be entitled to compensation by filing a lawsuit and we can help.

What’s the problem?

Manufactured and marketed by AstraZeneca, Prilosec is a prescription medication used to reduce the symptoms of gastroesophageal reflux disease, otherwise known as heartburn. Prilosec works by blocking the enzyme in the stomach wall that produces stomach acid. The reduction of stomach acid can make it harder for the body to absorb some nutrients including calcium, which can lead to weakened bones and fractures. A December 2006 study published in the Journal of the American Medical Association (JAMA) found that prolonged and/or heavy use of Prilosec significantly increases the risk of hip fractures in patients over the age of 50.

Prilosec Side Effects

Serious side effects most often reported in Prilosec users include the following:

  • Hip fractures
  • Wrist fractures
  • Spine fractures
  • Abdominal pain
  • Constipation
  • Nausea
  • Diarrhea
  • Stroke
  • Allergic reactions
  • Heart attack
  • Weight loss

The risk of these side effects is greatly increased in patients receiving high doses or in intervals greater than a year at a time. In March 2011, the U.S. Food & Drug Administration (FDA) updated an earlier drug safety communication indicating that it has determined that the use of high doses of PPIs for more than a year can increase the risk of osteoporosis and fractures of the hip, wrist and spine. In May 2010, the FDA announced that warnings would be provided about the risk of bone fracture side effects from prescription strength PPI drugs. The warnings came after FDA drug safety reviewers looked at a number of epidemiological studies into PPI bone fracture risks. Drugs affected by the labeling changes include:

Warning: Prilosec Can Interfere With Plavix

In November 2009, the FDA warned the public and healthcare professionals that individuals taking the anti-clotting drug Plavix should not take Prilosec and Nexium because they may lessen the effects of Plavix. This may prove problematic since approximately 50% of patients taking Plavix also take Nexium, Prilosec and other similar drugs to prevent stomach bleeding and ulcers, which are common side effects of taking Plavix. A previous study indicated that if you took PPI drugs like Prilosec, the risk of heart attack and stroke increased by 50%.

Do I have a Prilosec Lawsuit?

The Product Liability & Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Prilosec lawsuits. We are handling individual litigation nationwide and currently accepting new bone fracture cases in all 50 states.