Avandia Drug Description

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Avandia (rosiglitazone maleate) is an oral anti-diabetic agent which acts primarily by increasing insulin sensitivity. Avandia improves glycemic control while reducing circulating insulin levels.

Free Avandia Case Evaluation: If you or a loved one has been injured or died as a result of taking Avandia, you should contact our law firm immediately. You may be entitled to compensation by filing a lawsuit and we can help.

Chemically, rosiglitazone maleate is (±)-5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione, (Z)-2-butenedioate (1:1) with a molecular weight of 473.52 (357.44 free base). The molecule has a single chiral center and is present as a racemate. Due to rapid interconversion, the enantiomers are functionally indistinguishable.

The molecular formula is C18H19N3O3S•C4H4O4. Rosiglitazone maleate is a white to off-white solid with a melting point range of 122 to 123°C. The pKa values of rosiglitazone maleate are 6.8 and 6.1. It is readily soluble in ethanol and a buffered aqueous solution with pH of 2.3; solubility decreases with increasing pH in the physiological range.

Each pentagonal film-coated TILTAB tablet contains rosiglitazone maleate equivalent to rosiglitazone, 2 mg, 4 mg, or 8 mg, for oral administration. Inactive ingredients are: Hypromellose 2910, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol 3000, sodium starch glycolate, titanium dioxide, triacetin, and 1 or more of the following: Synthetic red and yellow iron oxides and talc.

Contact an Avandia Lawyer

Schmidt & Clark, LLP is currently accepting new Avandia cases throughout the entire United States. Our Defective Drug Litigation Group consists of highly experienced trial lawyers that focus exclusively on the representation of plaintiffs in Avandia lawsuits.

Again, if you or a loved one has been injured or died as a result of taking Avandia, you should contact our law firm immediately by using the form below. You may be entitled to compensation and we can help.