Avandia® Linked to Life-Threatening Side Effects
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Avandia (Overview)
Congestive Heart Failure
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Blindness, Vision Loss & Macular Edema
Bone Fractures
FDA Announcements
Manufacturers of Some Diabetes Drugs to Strengthen Warning on Heart Failure Risk
Avandia® (Generic: Rosiglitazone), a popular drug used by millions of Americans to treat Type 2 diabetes has been linked to the following life-threatening and serious side effects: congestive heart failure, heart attack, stroke, blindness, vision loss, macular edema, and bone fractures.
If you or a loved one have taken Avandia® and suffered any adverse side effects, you should contact us immediately. You may be entitled to compensation and we can help.
What is the problem?
The controversy surrounding Avandia® began when The New England Journal of Medicine (NEJM) published a combined analysis of more than 40 studies that evaluated approximately 28,000 Avandia® patients.
The results of the studies were shocking … One of the studies showed that Avandia®, made by GlaxoSmithKline, doubled the risks of heart failure and raised the risks of heart attack by 42 percent.
The main author of the NEJM article, Dr. Sonal Singh, has also stated, “In addition to its deleterious effects on the heart, Avandia® can cause blindness, and it doubles the risks of bone fractures in women.”
U.S. Food & Drug Administration “Black Box Warning”
After Dr. Singh’s article was published, the FDA stated that it had been evaluating the drug’s risks and issued a safety alert advising Avandia patients to consult their doctors.
The New York Times reported, “In the study’s aftermath, the drug agency said that it had been told in 2005 of a similar study conducted by GlaxoSmithKline, the manufacturer of Avandia that came to a similar conclusion. Critics denounced the agency’s delay in alerting patients.”
After a review of postmarketing adverse event reports, the FDA determined that an updated label with a boxed warning on the risks of heart failure was needed for the entire thiazolidinedione class of antidiabetic drugs.
The drugs affected by the FDA Black Box Warning are as follows:
- Avandia® (rosiglitazone maleate) Tablets
- Actos® (pioglitazone hydrochloride) Tablets
- Avandaryl® (rosiglitazone maleate and glimepiride) Tablets
- Avandamet® (rosiglitazone maleate and metformin hydrochloride) Tablets
- Duetact® (pioglitazone hydrochloride and glimepride) Tablets
The strengthened warning advises healthcare professionals to observe patients carefully for the signs and symptoms of heart failure, including excessive, rapid weight gain, shortness of breath, and edema after starting drug therapy. Patients with these symptoms who then develop heart failure should receive appropriate management of the heart failure and use of the drug should be reconsidered. People who have questions should contact their healthcare providers to discuss alternative treatments.
Avandia Side Effects
- Congestive Heart Failure
- Heart Attack
- Stroke
- Blindness
- Vision loss
- Macular Edema
- Bone Fractures
Do I have an Avandia Lawsuit?
The Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus exclusively on the representation of plaintiffs in Avandia lawsuits. We are handling individual litigation nationwide and currently accepting new Avandia cases in all 50 states.
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Avandia Side Effects & Lawsuit News (National)
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